Comparison of Two Mechanical Ventilation Modes on Oxygenisation

Comparison of Two Mechanical Ventilation Strategies on Tissue Oxygenization of Patients Undergoing Bariatric Surgery

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04389047

Enrollment

Registered

2020-05-15

Start date

2012-01-10

Completion date

2018-03-30

Last updated

2020-05-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bariatric Surgery Candidate, Hypoxia, Mechanical Ventilation, Tissue Damage

Keywords

bariatric surgery, tissue oxygenization, ventilation

Brief summary

Comparison the effect of two different mechanical ventilation modes on tissue oxygenization.

Detailed description

Aim of the study is to evaluate and compare the effects of two different mechanical ventilation modes as Volume Controlled Mechanical Ventilation (VCV) and Pressure Controlled Mechanical Ventilation (PCV) on non invasive tissue oxygenization levels of patients who scheduled for bariatric surgery.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 60 Years

Healthy volunteers

Inclusion criteria

Patients with Body Mass Index 35 - 50 kg/m2 Patients classified as American Society of Anesthesiologist (ASA) 1-2-3 classification Patients elected for Bariatric surgery

Exclusion criteria

Patients who wants to reject of study participation Patients who has any surgical complication during the surgery period Patients with decompensated cardiac failure Patients with Moderate or Severe obstructive/restrictive lung disease Patients with Reynaud disease Patients with Buerger phenomena Patients whıo has Intraoperative airway pressure more than 45 cmH2O Patients who had previous thoracic surgery Patients with Negative Modified Allen test

Design outcomes

Primary

Measure	Time frame	Description
Peripheral oxygen saturation-2	post operative 1.hour - 4. hour - 8. hour - 12. hour - 24.hour	Peripheral Oxygen Saturation (SpO2)
Arterial blood gas analysis	Peroperative 0. minute - 30. minute - 60. minute	Lactate, Ph, Arterial oxygen pressure, Arterial Carbondioxide pressure, Oxygen Saturation
Arterial blood gas analysis-2	post operative 1.hour - 4. hour - 8. hour - 12. hour - 24.hour	Lactate, Ph, Arterial oxygen pressure, Arterial Carbondioxide pressure, Oxygen Saturation
Peripheral oxygen saturation	peroperative 0. minute - 15. minute - 30. minute - 45. minute - 60. minute	Peripheral Oxygen Saturation (SpO2)
Oxygenization	peroperative 0. minute - 15. minute - 30. minute - 45. minute - 60. minute	Peroperative Non invazive technique of Superficial Tissue Oxygenization
Oxygenization-2	post operative 1. hour - 4. hour - 8. hour - 12. hour - 24.hour	Post operative Non invazive technique of Superficial Tissue Oxygenization

Secondary

Measure	Time frame	Description
Postoperative hemodynamic measurements	post operative 1.hour - 4. hour - 8. hour - 12. hour - 24.hour	Heart rate, Mean Arterial Blood Pressure
Carbondioxide	peroperative 15. minute - 30. minute - 45. minute - 60. minute	End tidal Carbondioxide measurement
Peroperative hemodynamic measurements	peroperative 0. minute - 15. minute - 30. minute - 45. minute - 60. minute	Heart rate, Mean Arterial Blood Pressure

Outcome results