Neuromyelitis Optica Spectrum Disorders
Conditions
Brief summary
The diagnostic cohort study could will be use to verify the clinical performance of the AQP4 -immunoglobulin G detection kit and whether it has a good correlation with the clinical diagnosis results. The applicability and accuracy of the kit in clinical diagnosis will be verified according to the measured data.
Interventions
None listed
Sponsors
MyBiotech Co. Ltd, China
Third Affiliated Hospital, Sun Yat-Sen University
First Affiliated Hospital of Fujian Medical University
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
14 Years to 80 Years
Healthy volunteers
Yes
Inclusion criteria
1. The patients who were diagnosed with NMOSD , and the cell-based assay was used to determine the AQP4-IgG-seropositive patients; 2. AQP4-IgG is negative in health people with age and sex matching and determined by cell-based assay; 3. Female or male, age 14-80; 4. Patients or authorized family members volunteered to participate in this study and signed informed consent.
Exclusion criteria
1. Patients with coagulation disorders; 2. Infection-related encephalitis; 3. Immune-related encephalitis; 4. A patient with severe mental illness who cannot cooperate clinically; 5. A patient with severe jaundice.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| results of AQP4 -immunoglobulin G detection kit | through study completion, an average of 6 months | The Serum test results of participants using AQP4 -immunoglobulin G detection kit |
Countries
China
Outcome results
None listed