Nasopharyngeal Sample, RT-PCR, Saliva Collection, Sars-CoV2
Conditions
Keywords
Sars-CoV2, RT-PCR, Saliva collection, nasopharyngeal sample
Brief summary
Since December 2019, the world has faced a pandemic of COVID-19, an infectious disease caused by SARS-CoV-2, a virus that emerged in China. The reference diagnosis is based on the search for the SARS-COV-2 genome in the nasopharyngeal sample. Carrying out this sample requires the competence of a healthcare professional and presents some inconveniences for the tested patient. Because saliva collection is simple, non-invasive, painless and inexpensive, and can be performed by poorly trained personnel, it could be an alternative to the reference nasopharyngeal sample. SARS-CoV2 detection in human saliva could be a potential diagnosis of COVID infection.
Interventions
None listed
Sponsors
Centre Hospitalier Universitaire, Amiens
Study design
Observational model
CASE_ONLY
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient hospitalized at the Amiens CHU in a COVID-19 unit * patient seen as outpatient in the area of infectious pathologies for COVID-19 infection
Exclusion criteria
* Patients under 18 * patients under guardianship or curators
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Detection of SARS-CoV-2 RNA in the saliva sample | day 1 | Detection of SARS-CoV-2 RNA in the saliva sample |
| Concordance between the Saliva sample and the nasonasopharyngeal sample SARS-CoV-2 RT-PCR results | day 1 | Concordance between the Saliva sample and the nasonasopharyngeal sample SARS-CoV-2 RT-PCR results |
Countries
France
Outcome results
None listed