Covid19, Sars-CoV2
Conditions
Keywords
ophthalmological lesions
Brief summary
The management of patients with SARS-CoV2 in respiratory distress can expose to corneal or retinal lesions induced by the stay in intensive care. Examination by ophthalmologists would make it possible to detect the most of the ophthalmologic problems known in intensive care and to provide an early, preventive or curative therapeutic response when possible, in order to avoid irreversible visual loss. The object of the research is to assess the presence and the importance of surface ophthalmologic lesions, the presence and the importance of retinal or optic nerve lesions, in order to improve the monitoring and primary prevention of this population
Interventions
PROCEDUREOphthalmologic exam
Direct exam and Slit lamp exam Shirmer test Retinophotography At inclusion, day 7, day 14 and discharge from hospital
Sponsors
Fondation Ophtalmologique Adolphe de Rothschild
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* patient SARS-CoV2 positive (RT-PCR or chest scanner) * hospitalized in intensive care
Exclusion criteria
* traumatic lesion of the face or any other condition preventing any ophthalmological evaluation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Describe ophthalmologic damage to the retina at day 7 | Day 7 | Retinophotography |
| Describe tear film anomalies at day 7 | Day 7 | Shirmer test |
| Describe tear film anomalies at day 14 | Day 14 | Shirmer test |
| Describe tear film anomalies at discharge of hospital | Discharge of hospital, up to 3 months | Shirmer test |
| Describe ophthalmologic damage to the retina at day 0 | Day 0 | Retinophotography |
| Describe ophthalmologic damage to the cornea with direct exam at day 0 | Day 0 | Direct exam |
| Describe ophthalmologic damage to the cornea with direct exam at day 7 | Day 7 | Direct exam |
| Describe ophthalmologic damage to the cornea with direct exam at day 14 | Day 14 | Direct exam |
| Describe ophthalmologic damage to the cornea with direct exam at discharge of hospital | Discharge of hospital, up to 3 months | Direct exam |
| Describe ophthalmologic damage to the cornea with slit lamp exam at day 0 | Day 0 | Slit lamp exam |
| Describe ophthalmologic damage to the cornea with slit lamp exam at day 7 | Day 7 | Slit lamp exam |
| Describe ophthalmologic damage to the cornea with slit lamp exam at day 14 | Day 14 | Slit lamp exam |
| Describe ophthalmologic damage to the cornea with slit lamp exam at discharge of hospital | Discharge of hospital, up to 3 months | Slit lamp exam |
| Describe tear film anomalies at day 0 | Day 0 | Shirmer test |
| Describe ophthalmologic damage to the retina at day 14 | Day 14 | Retinophotography |
| Describe ophthalmologic damage to the retina at discharge of hospital | Discharge of hospital, up to 3 months | Retinophotography |
| Describe ophthalmologic damage to the optic nerve at day 0 | Day 0 | Retinophotography |
| Describe ophthalmologic damage to the optic nerve at day 7 | Day 7 | Retinophotography |
| Describe ophthalmologic damage to the optic nerve at day 14 | Day 14 | Retinophotography |
| Describe ophthalmologic damage to the optic nerve at discharge of hospital | Discharge of hospital, up to 3 months | Retinophotography |
Countries
France
Outcome results
None listed