Preoxygenation
Conditions
Keywords
jet ventilation, supraglottic
Brief summary
The study assumed that supraglottic jet ventilation is an alternative solution as a safe way to do the preoxygenation before endotracheal intubation by contrasting it with mask pressurized ventilation. The investigators also expected that supraglottic jet ventilation won't increase the occurrence of esophageal reflux.
Detailed description
The study assumed that supraglottic jet ventilation is an alternative solution as a safe way to do the preoxygenation before endotracheal intubation by contrasting it with mask pressurized ventilation. The investigators also expected that supraglottic jet ventilation won't increase the occurrence of esophageal reflux. The investigators randomly divided the patients into 2 groups:Group C and Group S.Patients in Group C will be preoxygenation with mask pressurized ventilation while patients in Group S with supraglottic jet ventilation by Wei NASAL JET（WNJ）.The tracheal intubation will be done after the 3 minutes preoxygenation. The investigators will measure the PaCO2 before and after preoxygenation, and the investigators will take the stomach-ultrasonography to find if there are too much gas in the gastro. If pulse oximetry is lower than 95% during the preoxygenation, the investigators will adjust the position of the Wei NASAL JET（WNJ) or use the change the way that the investigators hold the mask or change the pressure of ventilation on the basis of the group.
Interventions
DEVICEsupraglottic jet ventilation
patients who were randomized into supraglottic jet ventilation group would be placed Wei Nasal Jet Tube after conducted. Then they will get the supraglottic jet ventilation to make sure their pulse oximetry is over 95%. After 3 minutes, endotracheal intubation was performed via mouth approach.
Sponsors
Peking University People's Hospital
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to 64 Years
Healthy volunteers
No
Inclusion criteria
* scheduled for any surgery under general anesthesia * adults age range from 18-64 years old * American Society of Anesthesiologists Physical Status Classification (ASA class) I-II * voluntary participation in this clinical trail, signed informed consents
Exclusion criteria
* patients with epistaxis, rhinostenosis, the episodes of rhinitis, severe gastroesophageal reflux disease, severe respiratory disease, severe cardiovascular and cerebrovascular disease * long-term use if anticoagulant drugs * can't cooperate with intervention * pulse oximetry \<95% with normal respiration
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| alveolar oxygen tension（PaO2） | 3 minutes after preoxygenation | The results comes from blood gas analysis |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| PaCO2 | 3 minutes after preoxygenation | The results comes from blood gas analysis |
| gastric antrum cross section | 3 minutes after preoxygenation | The results comes from the ultrasound of gastric |
| complications | 1 day | such as nasal bleeding, dry throat itching, sore throat, nausea and vomiting, pressure and other adverse reactions |
Countries
China
Contacts
Primary ContactHansheng Liang, MD
Outcome results
None listed