Acute Respiratory Distress Syndrome
Conditions
Keywords
ARDS, Covid-19, SARS-CoV-2, Inflammatory cytokine, Sepsis, ICU, Tbular necrosis, Ischemia, Pulmonary damage, Renal damage, Kidney damage
Brief summary
Renal damage in patients hospitalized for ARDS in the ICU can also be related to multiple causes including, but not limited to, the consequences of hemodynamic fluctuations in these patients or the use of nephrotoxic drugs responsible for acute post-ischemic or toxic tubular necrosis. Frequently observed abnormalities of cioagumation may also have a potential impact on renal structures, particularly glomerular capillaries. The researchers wish to characterize and phenotype the renal impairment of patients hospitalized in intensive care with tables of severe Covid19 infections in ARDS: clinical, biological and histological (by performing post-mortem biopsies). Translated with www.DeepL.com/Translator (free version)
Interventions
None listed
Sponsors
University Hospital, Strasbourg, France
Study design
Observational model
CASE_ONLY
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* Patients over 18 years of age * Diagnosed Covid-19 by RT PCR * Hospitalized in intensive care for management of complications related to Covid-19 from March 1, 2020 to April 20, 2020 * Patient not having expressed his or her opposition, after information, to the re-use of his or her data for the purposes of this research.
Exclusion criteria
\- Subject who expressed opposition to participating in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Analysis of Clinical, Biological and Histological Pulmonary and Renal Impairment Related to SARS-CoV-2 | 1 month |
Countries
France
Contacts
Primary ContactFerhat MEZIANI, MD, PhD
Backup ContactSaïd CHAYER, PhD, HDR
Outcome results
None listed