Genetic and Immunologic Basis of COVID-19 Infection

Genetic Factors Influencing the Response to Infection with SARS-COV-2

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04384250

Enrollment

500

Registered

2020-05-12

Start date

2020-06-01

Completion date

2024-12-30

Last updated

2025-03-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Genetic Basis of COVID-19 Infection

Keywords

SARS-COV-2, Genetics

Brief summary

We will study genetic factors causing severe disease due to infection with SARS-COV-2 which may help to find targeted therapy

Interventions

DIAGNOSTIC_TESTWhole Exome Sequencing

Genetic study of patients

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

1 Days to 50 Years

Healthy volunteers

Inclusion criteria

* severe COVID-19 infection

Exclusion criteria

* Comorbidity ((DM, hypertension, Chronic liver or Kidney diseases, HIV, morbid obesity, Malignancy, Immunosuppressive therapy)

Design outcomes

Primary

Measure	Time frame	Description
Mutations leading to increase susceptibility to SARS-COV-2 infection	12 months	Genetic susceptibility to COVID-19

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026