Agreement and Accuracy of Different Devices Corneal Measurements

Agreement and Accuracy of Different Devices for the Measurement of Corneal Thickness and Corneal Curvature in Patients With Keratoconus

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04383366

Enrollment

Registered

2020-05-12

Start date

2019-10-21

Completion date

2020-02-06

Last updated

2021-03-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Keratoconus

Brief summary

To compare repeatability, reproducibility and agreement of both, AS- OCT and Scheimpflug imaging, for the measurement of corneal curvature and corneal thickness in patients with keratoconus.

Interventions

DEVICEPentacam® (Oculus, Inc., Wetzlar, Germany)

Scheimpflug imaging

DEVICECasia II (Tomey Germany, Nürnberg)

Anterior segment optical coherence tomography

DEVICESpectralis Anterion (Heidelberg Engineering, Heidelberg, Germany)

Anterior segment optical coherence tomography

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 99 Years

Healthy volunteers

Inclusion criteria

* Men and women aged between 18 and 99 years * Presence of keratoconus * Signed informed consent

Exclusion criteria

* Contact lens history within 5 days * Pathologic changes of the lid or conjunctiva on slit-lamp examination * History of corneal ocular surgery/Previous corneal cross-linking

Design outcomes

Primary

Measure	Time frame
maximum K-value	1 day

Secondary

Measure	Time frame
Simulated minimum and maximum K-value	1 day
Mean K-values	1 day
Central Corneal thickness	1 day
Thinnest corneal point	1 day

Countries

Austria

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026