Children, Adult, COVID, Immune Deficiency, Immune Suppression, Infection
Conditions
Brief summary
A weekly questionnaire is sent to patients and parents of patients who are vulnerable for infections. Possible symptoms of COVID19 are asked for and use of healthcare services and testing for COVID19. Weekly reports are being send to the national institutions to update advice given to this group.
Detailed description
This study is designed to allow immunosuppressed children, their parents or adult patients to self-record their experiences of COVID-19 and other viral respiratory illnesses. Patients, parents and of immunosuppressed patients and patients aged 16-17 yrs will be provided with online information and asked to fill in online questionnaires at baseline and weekly thereafter. Information collected includes medication, symptoms, contact with health care providers, test results and impact on daily activities. Data will be collected and analysed weekly to be able to monitor any potential risk factors for severe disease. This study is complementary to, and not overlapping with, the global ISARIC World Health Organisation protocol that will be studying COVID-19 cases admitted to all National Health Service (NHS) Trusts, including all children.
Interventions
OTHERQuestionnaire
A weekly questionnaire will be filled in
Sponsors
Cambridge University Hospitals NHS Foundation Trust
Alder Hey Children's Hospital
Birmingham Children's Hospital
Bradford Royal Infirmary
Bristol Royal Hospital for Children
Cardiff and Vale University Health Board
Great North Children's Hospital
Great Ormond Street Hospital for Children NHS Foundation Trust
Oxford University Hospitals NHS Trust
Leeds Teaching Hospitals NHS Trust
Norfolk and Norwich University Hospitals NHS Foundation Trust
Nottingham Children's Hospital
Royal Alexandra Children's Hospital
Royal Hospital for Sick Children, Glasgow
Royal Manchester Children's Hospital
Royal Marsden NHS Foundation Trust
Northern Care Alliance NHS Group
Royal Sussex County Hospital
Sheffield Children's NHS Foundation Trust
St George's University Hospital National Health Service Foundation Trust
Swansea Bay University Health Board
University College London Hospitals
University Hospitals Coventry and Warwickshire National Health Service Trust
East Lancashire Hospitals National Health Service Trust
Imperial College Healthcare National Health Service Trust
National Heatlh Service Ayrshire and Arran
University Hospital Southampton NHS Foundation Trust
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Inclusion criteria
* Children part: Parent of immunosuppressed patient aged \<16 years or immunosuppressed patient aged 16-17 years * Adult part: Immunosuppressed patient aged \>17 years * Family or themselves able to complete the questionnaire which will be in English (due to current resources available translation will not be possible) * Reliable access to the internet
Exclusion criteria
* Unable to understand English
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| To describe COVID19 infection in children/adults who are vulnerable for infection in an outpatients setting | 1 year | To describe frequency of cough, fever, diarrhoea, shortness of breath, sore throat, blocked nose, red eyes, headache, joint pain, muscle pain, fatigue, chills, nausea, vomiting, diarrhoea over a year |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of children/adults tested positive for COVID19 | 1 year | Patient/parent reported positive tests for COVID19 |
| Number of children/adults admitted in hospital because of COVID19 | 1 year | Patient/parent reported admissions in hospital because of COVID19 |
| To assess the impact of COVID19 infection on the daily activities of immunosuppressed adults and children | 1 year | Patient/parent reported effect of COVID19 on daily activities |
Countries
United Kingdom
Outcome results
None listed