White Spot Lesion
Conditions
Keywords
Primary teeth, Enamel, Remineralisation
Brief summary
The present study aimed to compare the remineralisation capacity of white spot enamel lesions between two commercially available tooth pastes (Remin Pro and MI PASTE PLUS), applied at home twice a day on the anterior upper primary teeth by the patient and parents.
Detailed description
Objective: To evaluate and compare the clinical efficacy of Remin Pro® and MI Paste Plus® for the remineralisation of white spot lesions (WSL) on the enamel of primary teeth. Methods: The selected design for this study was a randomised double-blind clinical trial based on CONSORT guidelines. Patients with at least one upper anterior primary tooth with a WSL on the enamel surface, with units of fluorescence (UF) ranged from 11-20 (evaluated with DIAGNOdent) were included in the study. Patients were randomly assigned to receive either the twice-daily at-home topical application of Remin Pro® or MI Paste Plus® (both as experimental pastes) or Colgate Total® (as control paste). The degree of remineralisation was quantified by the change in the number of UF from the baseline evaluation and at days 10 and 21. The difference between groups was statistically evaluated using ANCOVA and ANOVA techniques.
Interventions
PROCEDURERemin Pro® and MI Paste Plus®
Te toothastes were applied at home twice a day over the six anterior upper primary teeth
Sponsors
Universidad Autonoma de San Luis Potosí
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Caregiver, Investigator)
Masking description
The three provided pastes had a similar physical appearance
Intervention model description
A randomised double-blind clinical trial, with three parallel study groups (two experimental and one control), whose participants were randomly assigned to one of te three groups.
Eligibility
Sex/Gender
ALL
Age
2 Years to 5 Years
Healthy volunteers
Yes
Inclusion criteria
* Young paediatric patients with at least one upper anterior primary tooth exhibiting one or several WSL on the smooth enamel surface. * Attending the Paediatric Dentistry Postgraduate Program's Clinic * Enamel lesions with units of fluorescence (UF) ranging from 11-20 as determined by DIAGNOdent * Signed Informed Consent
Exclusion criteria
* History of hypersensitivity to any of the compounds of the pastes * Enamel hypoplasia * Compromising systemic diseases
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Enamel remineralisation degree | 10 days | The remineralisation degree was quantified by the change in UF from the baseline (0 day) up to day 10 of twice-daily applications, by evaluation on the 10th day. |
Countries
Mexico
Outcome results
None listed