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Egg Consumption and Muscular Adaptations

Comparison of Whole Eggs vs. Egg Whites Consumption on Regulatory Myokines, Muscular Strength, Hypertrophy, Power and Body Composition.

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04381390
Enrollment
30
Registered
2020-05-08
Start date
2018-09-10
Completion date
2019-10-02
Last updated
2020-05-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertrophy

Brief summary

Eggs may be a viable alternative to various types of supplemental proteins given its similar ratings on various measures of dietary protein quality. The investigators hypothesis is that whole eggs would create a greater improvement in skeletal regulatory markers, hormonal responses and body composition than egg white ingestion in resistance-trained men.

Detailed description

The aim of this investigation was to compare the effects of whole egg versus egg white ingestion (daily and after training sessions) during 12 weeks of resistance training on skeletal muscle regulatory markers, hormonal responses and body composition in resistance-trained men. Specific aims of the study are to: To investigate the extent to which both whole egg and egg white ingestion will improve anabolic factors, fat free mass, fat mass and decrease catabolic markers after 12 weeks of resistance training in resistance-trained men.

Interventions

DIETARY_SUPPLEMENTWhole egg and resistance training

This intervention consisted of whole egg consumption concomitant with 12 weeks of resistance training. Subject ingested three whole eggs per day immediately after resistance training.

DIETARY_SUPPLEMENTEgg whites and resistance training

This intervention consisted of egg white consumption concomitant with 12 weeks of resistance training. Subject ingested an isonitrogenous quantity of six egg whites per day immediately after resistance training.

Sponsors

Tehran University
CollaboratorUNKNOWN
Alexei Wong
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
BASIC_SCIENCE
Masking
SINGLE (Investigator)

Eligibility

Sex/Gender
MALE
Age
18 Years to 30 Years
Healthy volunteers
Yes

Inclusion criteria

* performing resistance training at least three times a week for 1 year prior to the start of the study * not taking any dietary supplements or medications for at least 1 year prior to the start of the study * no known medical issues * no alcohol consumption or smoking for at least 1 year prior to the start of the study * no egg allergy/sensitivity.

Exclusion criteria

* non-willingness to continue nutritional or exercise protocols * participation in exercise other than the prescribed resistance training program * consumption of dietary supplement (other than egg) during the study period * Missing more than one resistance training session or post-exercise egg consumption throughout the study period

Design outcomes

Primary

MeasureTime frameDescription
Muscle mass12 weeksSkeletal muscle mass will be evaluated using computed tomography
Circulatory hormone levels12 weeksFasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentrations of testosterone, IGF-1, insulin and cortisol
Circulatory Myokines levels12 weeksFasting blood samples were collected from the antecubital vein using standard procedures and then analized to establish concentration of myostatin, follistatin, FGF-2, TGF-β1 and ACVA.
Body fatness12 weeksBody fat will be evaluated using bioelectrical impedance

Secondary

MeasureTime frameDescription
Muscular Strength12 weeksUsing 1 repetition maximum

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026