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Is Acupuncture Able to Reduce Nausea and Vomiting in the Terminal Ill Patient

Is Acupuncture Able to Reduce Nausea and Vomiting in the Terminal Ill Patient

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04378998
Enrollment
136
Registered
2020-05-07
Start date
2015-01-25
Completion date
2019-10-25
Last updated
2020-05-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Terminal Illness

Keywords

Acupuncture, Nausea, Vomiting, Palliative care

Brief summary

A comparative effectiveness research design was used. The sample size was calculated to 136 patients, who were randomized to an intervention group and a control group respectively. The patients were terminal ill patients enrolled to three in-bed hospices in Denmark and nausea and vomiting were measured using EORTC QlQ-c15-PAL (European Organisation for Research and Treatment of Cancer, Quality of Life Questionaire, core 15, Palliation)

Detailed description

The terminal ill patient is suffering from many different symptoms. In total 70% are suffering from nausea and vomiting due to the wide spread of cancer or due to side effects of treatment. Often the antiemetic's are not able to reduce symptoms to a level that enable the patient to experience quality in life in the last days of his life. The investigators had some experience with acupuncture as a complementary therapy but the investigators wanted more systematically to investigate if acupuncture is able to reduce the terminal ill patient´s nausea and vomiting. Literature show that acupuncture is able to reduce nausea and vomiting in patients receiving chemotherapy, but there is no literature that support the ability of acupuncture to reduce nausea and vomiting in the terminal ill patient. The purpose of this study was to generate evidence based knowledge close to practice regarding the effect of acupuncture in reducing nausea and vomiting in the terminal ill patient. Participants: Terminal ill patients suffering from nausea and/or vomiting Interventions: The intervention group received usual care plus acupuncture for three days. The acupuncture spots: Pericardium-6, Stomach-36, Liver-3 and Yin Tang were used. The control group received usual care.

Interventions

OTHERAcupuncture

The intervention group received usual care plus acupuncture for three days. The acupuncture spots: Pericardium-6, Stomach-36, Liver-3 and Yin Tang were used. The control group received usual care.

Sponsors

University of Aarhus
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Able to participate due to cognitive ability * Nausea * Admitted to in-bed hospice

Exclusion criteria

* Not able to participate due to cognitive impairment * Lymphedema in the area of acupuncture site

Design outcomes

Primary

MeasureTime frameDescription
Change in nausea scoreChange in nausea score from before intervention to three day after the interventionUsing EORTC QLQ-c15-PAL, the nausea item. Values: not at all, a little, quite a bit, very much. Very much is the worse outcome
Change in vomitingChange in vomiting from before intervention to four day after the interventionUnit of measure: Incidence of vomiting using the outcome measure question: Yes or No

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026