COVID-19 and ICU-acquired MDR Bacteria

Impact of SARS-CoV-2 Infection on the Incidence of ICU Acquired Colonization Related to Multidrug-resistant Bacteria

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT04378842

Acronym

COVID-BMR

Enrollment

368

Registered

2020-05-07

Start date

2020-05-18

Completion date

2021-07-26

Last updated

2026-04-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Critical Illness, Sars-CoV2

Keywords

Covid-19, Critically ill patients, multidrug-resistant bacteria, infection, colonization

Brief summary

This multicenter before-after study aimed to determine the impact of infection related to SARS-CoV-2 on the incidence of ICU-acquired multidrug resistant (MDR) bacteria.

Detailed description

Multicenter observational before-after study, aiming to determine the impact of infection related to SARS-CoV-2 on the incidence of ICU-acquired colonization and infection related to MDR bacteria.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* Expected ICU stay \> 48 hours * Rectal and nasal BMR screening performed \< 48 hours after admission to ICU

Exclusion criteria

* Patients aged \< 18 years Refusal to take part in the study ICU-stay \< 48 hours At least a second rectal and nasal BMR screening was not performed prior to ICU discharge (a posteriori exclusion criterion).

Design outcomes

Primary

Measure	Time frame	Description
Cumulative incidence of ICU-acquired colonization related multidrug resistant bacteria	from D3 until day 28 after ICU admission	percentage of patients with ICU acquired MDR bacteria colonization

Secondary

Measure	Time frame	Description
Cumulative incidence of ICU-acquired infection related to multidrug resistant bacteria	from D3 until day 28 after ICU admission	percentage of patients with ICU acquired MDR bacteria infection
Mechanical ventilation duration	from D1 until day 28 after ICU admission	the number of days Under mechanical ventilation
mortality	from D1 until day 28 after ICU admission	death in the ICU
length of stay in intensive care unit	from D1 until day 28 after ICU admission	the number of days of hospitalization in the ICU

Countries

France

Contacts

PRINCIPAL_INVESTIGATORSaad Nseir, MD,PhD

University Hospital, Lille

Outcome results