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The Effect of Pulse Flours on Blood Glucose, Satiety and Food Intake

The Effect of Food Formulated With Pulse Flours on Blood Glucose, Satiety and Food Intake

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT04378374
Enrollment
54
Registered
2020-05-07
Start date
2019-09-16
Completion date
2022-12-31
Last updated
2023-03-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appetite, Blood Glucose, Eating, Food

Keywords

Pulses, Flour, Food Intake, Satiety, Blood Glucose

Brief summary

Pulse flours represent a fast-growing segment on the functional food market; however, their health effects are not well understood. The observational studies and acute trials have established the link between frequent consumption of cooked whole pulses (beans, peas, lentils and chickpeas) and healthier body weight and improved blood glucose control. However, it is not clear whether these effects still remain after the processing of pulses into flours. The investigators hypothesized that the baked food products formulated with lentil flour of the same particle size as all-purpose wheat flour may reduce postprandial glycaemia and elicit a stronger suppression of subjective appetite due to its higher content of protein and resistant carbohydrate compared to all-purpose wheat flour. The treatments will be formulated either with lentil flour or with all-purpose wheat flour of similar particle size or with their combination. The objective of the project is to test the effect of foods formulated with lentil flour and/or wheat flour on blood glucose, short-term food intake and subjective appetite.

Interventions

OTHERFood-1

Baked food made of lentil flour

OTHERFood-2

Baked food made of lentil flour and wheat flour

OTHERFood-3

Baked food made of wheat flour

OTHERFood-4

Potable water (energy and carbohydrate-free control)

Sponsors

Mount Saint Vincent University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
BASIC_SCIENCE
Masking
DOUBLE (Subject, Investigator)

Masking description

The participants and investigators are blinded and could not distinguish the food formulated with different flours. The taste and flavour in all treatments were similar due to added flavourings.

Eligibility

Sex/Gender
ALL
Age
19 Years to 35 Years
Healthy volunteers
Yes

Inclusion criteria

* Healthy young male and female adults (19-35 y) with body mass index (BMI) of 20.0-24.9kg/m2

Exclusion criteria

* Breakfast skippers * Smokers (including e-cigarettes) / cannabis consumers * Those with BMI \< 18.5 and \> 24.5 kg/m2 * People with chronic diseases * People with impaired blood glucose control * People taking medication that may affect central and peripheral mechanisms of food intake regulation, blood glucose control, cognitive performance and sedative medication. * People with intellectual disabilities (excluded due to their inability to comprehend hedonic and visual analogue scales used in the study). * People with food allergies or gastrointestinal disorders (e.g., IBS and others).

Design outcomes

Primary

MeasureTime frameDescription
Blood Glucose0-120 minutesThe concentration of venous blood glucose before and after each treatment consumption
Food Intake120 minutesThe amount of energy (kcal) consumed ad libitum at the test meal (pizza lunch) two hours after each treatment consumption
Subjective Appetite0-120 minutesThe subjective assessment of appetite parameters including desire to eat, fullness, hunger and a prospective food consumption measured with 100 mm Visual Analogue Scales with two opposite statements at each end (e.g., for the hunger scale, 0 mm means not hungry at all, and 100 mm means very hungry).

Secondary

MeasureTime frameDescription
Physical Comfort0-120 minutesThe subjective assessment of wellness and gastrointestinal symptoms including a feeling of nausea, diarrhea, flatulence, and other parameters measured with 100 mm Visual Analogue Scales with two opposite statements at each end.
Palatability of Food5 minutesThe palatability of the treatments will be measured immediately after consumption with a 100 mm Visual Analogue Scale with two opposite statements at each end or with a 9-point hedonic scale.

Countries

Canada

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026