Durable Mechanical Support Device, Heart Failure, Left Ventricular Assist Device, Prognosis
Conditions
Brief summary
A biobank has been created to investigate the prognostic value of biomarkers (mainly BNP) in patients implanted with durable mechanical assist devices comparing patients with advanced HF supported by MCS with those who are transplanted and those who remain on optimal medical therapy. Patients will be followed up for 25 years after inclusion.
Detailed description
All patients referred for advanced HF treatment at the Dept of Cardiology at Rigshospitalet.
Interventions
OTHERObservation. No intervention per se.
Observation. No intervention (no collection of blood).
OTHER2) Observation and collection and of blood sample
All patients evaluated for adv HF (HTX/LVAD) will be offered to contribute to this database; Blood samples will be collected from all at baseline. Patients receiving LVAD will contribute on a yearly basis (or until withdrawal of consent). For other patients no further blood will be collected unless they receive an LVAD at a later point.
Sponsors
Rigshospitalet, Denmark
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Inclusion criteria
* All patients referred for evaluation for advanced HF treatment at the Rigshospital in Denmark * Age\>18 years
Exclusion criteria
* No consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Alive | 25 years from inclusion | — |
| Dead | 25 years from inclusion | Dead after inclusion in study |
Countries
Denmark
Contacts
Primary ContactKiran Mirza, MD
Backup ContactFinn Gustafsson, MD, PhD, DMSci
Outcome results
None listed