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Colchicine Has Anti-diabetic Effect

Colchicine Has Anti-diabetic Effect and May be an Option for Type 2 Diabetes Management

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04377321
Enrollment
150
Registered
2020-05-06
Start date
2019-10-10
Completion date
2020-05-02
Last updated
2020-05-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Treatment Adherence

Keywords

type 2 diabetes, colchicine, inflammatory markers

Brief summary

Colchicine has antidiabetic effect and may be an option for type 2 diabetes management

Detailed description

Observational cohort prospective study with following of 150 newly diagnosed type 2 diabetes patients who were in 3 groups, had been monitored in a private clinic, each group 50 patients number, with 30 females and 20 males after written consent from all patients. The ages of all patients were between 35 and 55 years. The aim of this study was to evaluate colchicine effect on A1C of newly diagnosed type2 diabetes compared to the metformin and control group on diet only. The first group patients received colchicine 0.5twice daily for 6 months, the second group received metformin 1gm twice daily, the third group patients were on diet only. During the period of treatment, the investigators followed the patients if there were side effects of the drugs used. No side effects were monitored during the period of treatment except for gastric upset in some patients using metformin

Interventions

colchicine tabletes for 6 months

Sponsors

Ministry of Health and Population, Egypt
Lead SponsorOTHER_GOV

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
35 Years to 55 Years

Inclusion criteria

* type 2 diabetes newly diagnosed age 35- 55 years

Exclusion criteria

* severe anemia hypothyroidism and hyperthyroidism moderate to severe liver or kidney disease

Design outcomes

Primary

MeasureTime frameDescription
colchicine for treatment of type diabetes patients6 monthscolchicine tablets .5 mg twice daily for 6 months

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026