Bone Resorption, Tooth Loss
Conditions
Keywords
tooth extraction, ridge preservation, hyaluronic acid, dental implant
Brief summary
The aim of this study is to test the hyaluronic acid hydrogel impact on the healing acceleration of xenogenic bone substitutes used in ridge preservation. Following tooth extraction, bone particles are mixed with the hyaluronic acid gel and grafted in the tooth socket. at the implant placement phase, a cone beam computer assisted tomography file is recorded in order to compare it with the baseline and a biopsy to evaluate the histological consequences.
Interventions
PROCEDURERidge preservation: Tooth extration and immediat bone grafting in the socket
Following the tooth extraction, the socket is filled with a mixture of xenogenic bone and hyaluronic acid and sealed with an epithelio-connective arrested from the maxillary palate
Sponsors
Saint-Joseph University
Study design
Allocation
NON_RANDOMIZED
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes
Inclusion criteria
* Patients in need of tooth extraction and willing to receive dental implants in the extraction site * Presence of two mono radicular teeth in need of extraction
Exclusion criteria
* Patients with systemic diseases * Patients under 8 years and above 60 years. * Presence of endodontic or periodontal lesion in the extraction sites
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Radiological assessement of the boe resorption | 4 months | the baseline if the CBCT is compared to the 4 months post-op to assess the bone resorption |
| Histomorphometric analysis | 4 months | During implant placement, a bone biopsy is harvested and stained with different colorants to assess microscopically the biological healing |
Countries
Lebanon
Outcome results
None listed