The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery

The Effect of Regional Anesthesia Techniques on Brain Tissue Oxygenation in Thoracic Surgery Operations Where Single Lung Ventilation is Applied

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04373174

Enrollment

Registered

2020-05-04

Start date

2020-05-01

Completion date

2021-05-15

Last updated

2023-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thoracic Surgery, Epidural Anesthesia, Cerebral Oxygen Saturation

Brief summary

Today, it is preferred that the lung with pathology for thorax surgery is not under ventilation during operation in terms of reliability and ease of operation. For this reason, the anesthesia approach is characteristic and it is ensured that the single lung is not ventilated during the operation by means of specially manufactured intubation tubes. This application can disrupt tissue oxygenation due to both Operation position and single lung ventilation. Thoracic epidural analgesia, which is applied as the gold standard of Thoracic Surgery, is applied prior to the operation and is provided to assist in postoperative analgesia.

Detailed description

The aim of this study was to investigate the effect of thoracic epidural analgesia method on brain tissue oxygenation in patients with single lung ventilation.

Interventions

DEVICERegional oximetry probe

Regional oximetry probe will be placed in the frontal area of the head

PROCEDUREThoracic Epidural block

Thoracic epidural block will be applied to the patients before the operation begins

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

PREVENTION

Masking

SINGLE (Subject)

Intervention model description

prospective,randomized

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Patients who were in the American Society of Anesthesiologists (ASA) I-III class * Underwent Thoracic Surgery

Exclusion criteria

* Local anesthetic allergy, * Bleeding is a diathesis disorder * Allergic to the drugs used, * Patients who are not reluctant to participate in the study, * Presence of infection in the block area, * Patients whose body mass index is over 30

Design outcomes

Primary

Measure	Time frame	Description
rso2	peroperative 2 hours	Regional oximetry probe will be placed in the frontal area of the head

Secondary

Measure	Time frame	Description
po2	peroperative 2 hours	Arterial blood gas oxygen pressure
ETCO2	peroperative 2 hours	End-tidal carbon dioxide (ETCO2) level

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026