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Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy

Predicting Risk Factors of Postoperative Hypocalcemia After Total Thyroidectomy: is Safe Discharge Without Supplementation Possible?

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04372225
Enrollment
477
Registered
2020-05-01
Start date
2020-04-25
Completion date
2020-04-25
Last updated
2020-05-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypoparathyroidism

Keywords

thyroidectomy, hypocalcemia, hypoparathyroidism, discharge, PTH

Brief summary

With increasing economic pressures to shorten the length of hospital stay, there has been much recent interest in studying risk factors for the development of postoperative hypocalcemia. The aim of this study was to investigate in patients undergoing total thyroidectomy whether serum calcium and/or PTH levels can predict hypoparathyroidism.

Detailed description

Our study consists of analyzing the calcium (mmol/l) and PTH (pmol/l) levels on the first postoperative day. Postoperative treatment with calcium and vitamin D and the length of hospital stay is also taken into consideration. We also analyze post-operative complications.

Interventions

OTHERanalysis of hypocalcemia

analysis of postoperative calcium and PTH levels

Sponsors

Aix Marseille Université
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
Yes

Inclusion criteria

• Total thyroidectomy

Exclusion criteria

* concomitant parathyroidectomy for primary hyperparathyroidism * lobectomy only * completion thyroidectomy * central and lateral neck dissection * patients with calcium and/or vitamin D supplementation prior surgery * patients with known and significant osteoporosis and renal failure

Design outcomes

Primary

MeasureTime frameDescription
calcium and PTH thresholdsone yearsFor all 477 patients postoperative calcium and PTH levels and treatment with calcium and vitamin D will be analyzed. Objective is to identify the calcium and PTH thresholds at which the patient after total thyroidectomy can be discharged without risk of hypocalcemia.

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 21, 2026