Postoperative Complications
Conditions
Keywords
muscle relaxant, general anesthesia, Chinese patient
Brief summary
Muscle relaxant is usually needed for surgery. However, the optimal depth of neuro-muscular blockade is still on debate. Deep neuro-muscular blockade may benefit the patients during surgery, but may increase the risk of residual blockade after surgery. Residual blockade has been reported to increase risk of morbidity. In this study, we tend to observe the postoperative outcomes in patients undergoing abdominal surgery under general anesthesia. And to compare the outcomes in patients received different depth of neuro-muscular blockade.
Interventions
OTHERNo Response to Train of Four Stimulation
No response is observed during Train of Four stimulation monitoring during surgery
OTHER1-2 Response to Train of Four Stimulation
1 to 2 response is observed during Train of Four stimulation monitoring during surgery
Sponsors
Air Force Military Medical University, China
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No
Inclusion criteria
* Age ≥18 years old * Body mass \<18 kg/m2 * American Society of Anesthesiologists status I-II * Patients scheduled for elective laparoscopic colorectal or urological surgery * Patients received general anesthesia and muscle relaxant * Patients with written informed consent.
Exclusion criteria
* Second surgery during the same admission. * Outpatient surgery * Retroperitoneal laparoscopic surgery * Patients scheduled for mechanical ventilation after surgery * Patients scheduled for muscle relaxant other than rocuronium * Patients with pregnancy or planned for breeding * Patients who are involved in other studies
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Visual Analogue Scale of pain at rest at 24 hours after surgery | from end of surgery to 24 hours after surgery | The intensity of pain is reported by the patient by provide a number between 0 and 10. 0 means no pain, and 10 means unbearable pain. Higher score means stronger pain. |
| Visual Analogue Scale of pain at cough at 24 hours after surgery | from end of surgery to 24 hours after surgery | The intensity of pain is reported by the patient by provide a number between 0 and 10. 0 means no pain, and 10 means unbearable pain. Higher score means stronger pain. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Time to extubation of the endotracheal tube | from end of surgery to removal of the endotracheal tube, on an average of 15 minutes | — |
| Incidence of patients suffering pain at 24 hours after surgery | from end of surgery to 24 hours after surgery | — |
| Satisfaction score of the Surgeon to the condition during surgery | from start of surgery to end of surgery, on an average of 2.5 hours | The satisfaction of the Surgeon is measured by a scale from 0-10. 0 is for extremely unsatisfied, 10 is for totally satisfied. Higher score means higher satisfaction. The surgeon is asked to give a number between 0 and 10 to describe his satisfaction. |
| Incidence of major postoperative complications | from end of surgery to discharge from the hospital, on an average of 5 days | Incidence of major postoperative complications (including myocardial ischemia, pulmonary infection, respiratory failure, brain ischemia) |
| Time to flatus | from end of surgery to flatus, on an average of 3 days | — |
Countries
China
Outcome results
None listed