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PREDICT: Thinking About Pregnancy Risk in Women With Kidney Disease

Understanding Perception of Risk in Pregnancy Associated Progression of Chronic Kidney Disease

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04370769
Acronym
PREDICT_RP
Enrollment
115
Registered
2020-05-01
Start date
2020-10-16
Completion date
2022-03-31
Last updated
2021-09-05

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Kidney Diseases, Pregnancy Related

Keywords

Risk perception

Brief summary

Currently, there is no robust evidence about how women with Chronic Kidney Disease (CKD) perceive pregnancy risk. The aims of this research are to understand women with CKD's perception of risk in pregnancy. In order to provide appropriate pre-pregnancy and antenatal counselling including accurate presentation of risk of pregnancy outcomes, it is important to establish how do women with CKD perceive their risk in pregnancy. In addition, to facilitate discussion about pregnancy for women with CKD, it is critical to understand key psychosocial factors influencing their risk perceptions. This study will be conducted in two phases. In phase one, risk perceptions in women with CKD who are contemplating pregnancy will be quantitatively measured with potential influencing psychosocial factors including their illness perceptions, quality of life, anxiety, depression and perceived social support. Demographic, pregnancy-intentions, medical and pregnancy histories will also be collected. Phase one findings will establish to what extent do women with CKD perceive their pregnancy risk. In phase two, perception of risk, pregnancy intention and behaviour, will be qualitatively explored in women with CKD who perceive high and low degrees of risk. This sub-study will facilitate understanding about which factors and experiences impact risk perception and their relationship with pregnancy intentions and behaviour.

Detailed description

The objectives for this research are: 1. To understand how women with CKD perceive their pregnancy risk. 2. To examine the associations between biopsychosocial factors (demographics, psychosocial factors, renal and pregnancy history) and women with CKD's perception of risk in pregnancy. 3. To examine the relationship between pregnancy-related intention and perception of pregnancy risk in women with CKD. 4. To gain an in-depth understanding of the biopsychosocial factors which influence risk perception and pregnancy-related behaviour, in women with CKD who perceive high and low risk perceptions. To achieve these objectives this study is divided into two phases: Phase 1: Quantitative assessment of risk perception and biopsychosocial factors in women with CKD Phase 2: Qualitative exploration of risk perception in women with CKD with high and low risk perception scores

Interventions

None listed

Sponsors

King's College London
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 60 Years
Healthy volunteers
No

Inclusion criteria

* Diagnosed with CKD stages 1-5 according to KDOQI guidelines) * ≥18 years old * Planning a pregnancy * Adults who have the capacity/capability to provide fully informed consent for the study

Exclusion criteria

* Already established on haemodialysis or peritoneal dialysis * Women \< 18 years old or \>50 years old * Inability or unwilling to give informed consent * Does not speak English

Design outcomes

Primary

MeasureTime frameDescription
Pregnancy intentionBaseline (Pre-pregnancy)Measuring women's pregnancy intention using standardised measure (Desire to Avoid Pregnancy Questionnaire)
Risk perception of pregnancy risk (Perception of Pregnancy Risk Questionnaire)Baseline (Pre-pregnancy)Measuring women's perception of pregnancy risk.

Countries

United Kingdom

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 9, 2026