General Anesthesia
Conditions
Keywords
electroencephalography, etomidate, propofol
Brief summary
Electroencephalography (EEG) monitoring reflect the brain electro-activity. Different anesthetics may show different changes in EEG during anesthesia. Etomidate and propofol are widely used for general anesthesia. The characteristic changes of these two anesthetics may be different.
Interventions
DRUGetomidate anesthesia
etomidate is used for induction and maintenance of general anesthesia
propofol is used for induction and maintenance of general anesthesia
Sponsors
Air Force Military Medical University, China
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients scheduled for surgery under general anesthesia * Patients provided written informed consent
Exclusion criteria
* Patients with history of neurological or psychiatric diseases * Patients younger than 18 years old * Patients scheduled for surgery involved head * Patients with pregnancy or planned for breeding
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| delta wave deficiency during anesthesia | from anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours |
Secondary
| Measure | Time frame |
|---|---|
| spindle wave deficiency during anesthesia | from anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours |
| burst suppression during anesthesia | from anesthesia induction to extubation of the endotracheal tube, on an average of 2.5 hours |
Countries
China
Contacts
Primary ContactZhihong Lu
Outcome results
None listed