COVID-2019 Pneumonia, Pulmonary Rehabilitation
Conditions
Brief summary
The noval coronavirus disease 2019 (COVID-19) would cause physical and psychological dysfunctions in infected patients. We expect that an intelligence-based remote pulmonary rehabilitation scheme could improve patients' health status after hospital discharge. The intelligence-based remote pulmonary rehabilitation program is designed in a real-world and prospective manner, aiming to evaluate the efficacy of rehabilitation among 200 patients in the epicenter of China (Wuhan City) according to their varied adherence. An eight-week rehabilitation scheme, including two weeks for physicians and physiotherapists remotely guided training, and six weeks for patient self-management, will be addressed. The primary outcome of current study is six-minute walking distance and lung function, and secondly respiratory muscle strength, physical fitness assessment, symptoms and quality of life, etc. will also be assessed. Recruited patients will be followed up at week 2, 4, 8 after enrollment and at month 1, 3, 6, 12 after the rehabilitation training completed, respectively. The study has been approved by the ethics committee of China-Japan Friendship Hospital and three participating centers in Wuhan City.
Interventions
BEHAVIORALRemote pulmonary rehabilitation
The pulmonary rehabilitation intervention includes respiratory exercise, barehanded aerobic training, exercise prescription of elastic band impedance training, respiratory muscle strength training, etc.
Sponsors
Wuhan lung Hospital
Wuhan Central Hospital
Wuhan University
Ai You Foundation
China-Japan Friendship Hospital
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
20 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* patients diagnosed as COVID-19 pneumonia according to the Chinese diagnostic criteria (Trial 7th Edition), aged 20 years or above; * patients who did not participate in any other rehabilitation training scheme; * patients who did not participate in any other intervention clinical trials; * patients who signed the informed consent and were able to adhere to a long-term follow-up for at least one year.
Exclusion criteria
* pregnant women; * patients with previous mental disorders or undergoing mental health treatment; * patients with previous personality disorder, intelligence disorder, brain injury or brain disease; * patients with serious cardiovascular, cerebrovascular, neuromuscular and other systemic diseases or other diseases affecting physical activity; * patients with tumors and underwent treatment. One will be considered as withdrawal if consent is revoked, lost to follow-up, or unable to take the pulmonary rehabilitation scheme due to severe exacerbation, comorbidities, injury or trauma, etc.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Six-minute walking distance (6MWD) | One year | Walking distance within six minutes |
| Pulmonary function | One year | Forced expiratory volume in one second (FEV1), forced vital capacity (FVC), etc. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Symptom | One year | Modified British Medical Research Council (mMRC) dyspnea scale, etc. |
| Psychological evaluation | One year | Self-training depression scale (SDS) and self-rating anxiety scale (SAS) |
| Respiratory muscle strength | One year | Maximal inspiratory pressure, maximal expiratory pressure, etc. |
| Physical activity | One year | International physical activity questionnaire (IPAQ) |
| Proportion of returning to society | One year | Proportions of returning to routine work and normal life |
| Quality of life | One year | 36-item short-form health survey (SF-36), etc. |
| Physical fitness assessment | One year | Two-minute walking test, short physical performance battery, grip strength of both upper limbs, knee extension strength of both lower limbs, etc. |
Countries
China
Contacts
Primary ContactGeyi Wen, Resident
Backup ContactLulu Yang, Resident
Outcome results
None listed