Intensive Care Unit, Muscle Weakness, Respiratory Insufficiency
Conditions
Keywords
Low serume creatinine levels, respiratory insufficiency, ICU
Brief summary
Low creatinine levels may be a sign of muscle atrophy or weakness, and therefore predictive for respiratory insufficiency in the Intensive care unit (ICU) patients. The investigators compared the outcomes of participants with low creatinine levels with subsequent ICU participants admitted into ICU in the tertiary hospital.
Detailed description
The investigators have found a total of 46 participants with low creatinine levels and compared their outcome data with a group of participants with normal or high creatinine levels (control group, N=61). Low creatinine was defined as values of ≤40 μmol/L. Demographic data, type of admission (medical vs. surgical), hemoglobin values, CRP, and ventilator days were compared. A statistical analysis was performed using chi square and T-test.
Interventions
DIAGNOSTIC_TESTSerum creatinine levels
Comparison of treatment length using mechanical ventilaton, length of stay in ICU, survival between two groups
Sponsors
Josip Juraj Strossmayer University of Osijek
Osijek University Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Inclusion criteria for study group was value of ≤40 µmol/L serume creatinine level during hospitalization in ICU from July 2015 to November 2016.
Exclusion criteria
* Patients who were younger than 18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Length of mechanical ventilation treatment in group with low serume creatinine level | Through study completion, an average of 1 year | The investigators compared length of mechanical ventilation treatment between group with low serume creatinine level and control group |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| White blood cell values in group with low creatinine level | Through study completion, an average of 1 year | The investigators compared white blood cell values between group with low creatinine level and control group |
| Hemoglobine values in group with low creatinine level | Through study completion, an average of 1 year | The investigators compared hemoglobine values between group with low creatinine level and control group |
| Number of patients who started nutrition in ICU | Through study completion, an average of 1 year | The investigators compared number of patients between group with low creatinine level and control group who started nutrition in ICU |
| Length of stay in ICU in group with low serume creatinine level | Through study completion, an average of 1 year | The investigators compared length of stay in ICU between group with low serume creatinine level and control group |
| Number of patients who receive blood products transfusion | Through study completion, an average of 1 year | The investigators compared number of patients who received blood products between group with low creatinine level and control group |
| Number of patients discharged | Through study completion, an average of 1 year | The investigators compared number of patients who were discharged from intensive care unit to the ward between group with low creatinine level and control group |
| Platelets values in group with low creatinine level | Through study completion, an average of 1 year | The investigators compared platelet values between group with low creatinine level and control group |
Countries
Croatia
Outcome results
None listed