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ARMOR Study: COVID-19 Seroprevalence Among Healthcare Workers

SARS-CoV-2 Seroprevalence Among Healthcare Workers: ARMOR Study Demonstration Project

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04367857
Enrollment
1000
Registered
2020-04-29
Start date
2020-04-18
Completion date
2027-02-01
Last updated
2026-04-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus, Coronavirus Infection, Covid-19

Brief summary

The novel coronavirus (SARS-CoV-2) has spread all around the world and testing has posed a challenge globally. Health care providers are highly exposed and are an important group to test. On top of these concerns, health care workers are also stressed by the needs on responders in the COVID-19 crisis. The investigators will look at different ways to measure how common COVID-19 is among health care workers, how common is the presence of antibodies by serological tests (also known as serostatus). The investigators will describe health worker mental and emotional well-being and their coping strategies in their institutional settings. Lastly, the investigators will describe how knowing serostatus can affect individuals' mental and emotional well-being and how to cope in the midst of the COVID-19 response. This will help to how to better test and help healthcare workers in the COVID-19 pandemic and prepare for possible future outbreaks.

Detailed description

The rapid spread of the novel coronavirus SARS-CoV-2 has resulted in pandemic levels and a global challenge in diagnosing infection. Diagnosing infection, defining recovery and immunity has been challenging. Health care providers in particular are very interested in knowing their status as they are highly exposed, and if infectious, can potentially transmit infection nosocomially (in the healthcare workplace setting) and to their household. In addition to understanding their exposure risk, infectious period, and immunity status, health care workers are reporting high levels of psychosocial distress including anxiety and burnout. The investigators aim to assess the baseline and cumulative seroprevalence of SARS-CoV-2 among health care workers using both quantitative and qualitative serological assays; describe psychosocial well-being and coping strategies among health workers in their institutional settings and describe how knowledge of one's serostatus affect psychosocial well-being, and coping strategies. Findings from this study will inform; 1) use of serological assays and testing algorithms, and 2) approaches to manage psychosocial stress for healthcare workers.

Interventions

Quantitate Serology enzyme-linked immunosorbent assay (ELISA) for COVID-19

BEHAVIORALHealth Care Worker Survey

The purpose of this survey is to assess how healthcare workers are experiencing and coping with the COVID-19 crisis.

Sponsors

Columbia University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* 18 years of age or older * NewYork-Presbyterian (NYP) healthcare personnel employee or affiliate * Understands and reads English

Exclusion criteria

* Younger than 18 years of age * Mentally and/or physically unable to complete study requirements

Design outcomes

Primary

MeasureTime frameDescription
Proportion seropositiveUp to 12 months after collection visitPercentage of health care workers with positive serological markers to describe patterns in exposure, re-infection, clinical symptom, serological responses among health care workers based on their baseline serological status over a one year period.

Countries

United States

Contacts

CONTACTBrett Gray
bg2168@cumc.columbia.edu212-305-1570
PRINCIPAL_INVESTIGATORMagdalena Sobieszczyk, MD, MPH

Columbia University

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Apr 9, 2026