COVID, RT-ddPCR Multiplex
Conditions
Brief summary
The objective of the study is to develop and validate a molecular diagnostic strategy (RT-ddPCR multiplex) of COVID-19 based on a saliva sample and alternative to the RT-qPCR method, in order to : 1. to compensate for the risk of a shortage of diagnostic kits, reagents and materials necessary for molecular diagnosis; 2. to increase the molecular diagnostic capacity of COVID-19 at the Rouen University Hospital; 3. and to have a method compatible with screening extended to populations at risk.
Interventions
DIAGNOSTIC_TESTSaliva collection
Saliva collection will be done in addition to standard diagnosis collection (nasopharyngeal collection using swab)
Sponsors
University Hospital, Rouen
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Person aged over 18 years presenting to the COVID-19 consultation of the Rouen University Hospital for screening * Person affiliated to a social security scheme
Exclusion criteria
* Person objecting to participation in the research after reading information * Person under the protection of justice, * Person deprived of their liberty by administrative or judicial decision (guardianship, curatorship, etc.) * Patient under guardianship or curatorship
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of positive patient using saliva method compared to number of positive patient using standard method | One hour |
| Number of negative patient using saliva method compared to number of negative patient using standard method | One hour |
Countries
France
Contacts
PRINCIPAL_INVESTIGATORThierry FREBOURG, Pr
University Hospital, Rouen
Outcome results
None listed