Acute Pain, Analgesia, Chronic Pain
Conditions
Keywords
Regional Anesthesia, Acute and chronical pain, Quadratus Lumborum Blocks, Cesarean Section, Spinal Anesthesia
Brief summary
This study evaluates the post-operative analgesic effects of quadratus lomborum block 2 and 3 (QLB 2, 3) in patients having cesarean section with spinal anesthesia. Spinal anesthesia will be performed to all patients for the surgery.
Detailed description
In this study, patients are divided into two groups. After the spinal anesthesia is performed and cesarean section surgery is over; QLB 2 block will be performed to patients in Group A ; while QLB 3 block will be performed to patients in Group B. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively. Group A - Patients in group A will have QLB 2 block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively. Group B - Patients in group B will have QLB 3 block after the surgery. In addition, patient controlled analgesia (PCA) will be used in the first 24 hours postoperatively.
Interventions
OTHERRegional anesthesia
The effects of QLB 2, 3 interfascial plane blocks on post-operative analgesia after cesarean section surgery
Sponsors
Ondokuz Mayıs University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
QUADRUPLE (Subject, Caregiver, Investigator, Outcomes Assessor)
Masking description
The anesthesia doctor who will perform the interfascial plane block (QLB 2, 3) will be informed with a sealed envelope by an independent assistant outside the study, and the patient will not know which block is performed.
Intervention model description
Randomization of the study will be done by a doctor who will not participate in patient follow-up with closed envelopes using computer generated randomization codes.
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* Being pregnant for at least 37 weeks * Planning an elective cesarean operation * Being between the ages of 18-45
Exclusion criteria
* ASA 3-4 patients with comorbitidies (Serious renal, cardiac, hepatic disease) * Being operated with general anesthesia * Obesity (\> 100 kg, BMI\> 35 kg / m2) * Contraindication of regional anesthesia (quagulopathy, abnormal INR, thrombocytopenia, infection at the injection site) * Hypersensitivity to local anesthetics or a history of allergy * Patients with a history of opioid use longer than four weeks * Patients with psychiatric disorders * Patients with anatomic deformity * Patients who do not want to participate
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Opioid consumption in the first 24 hours after surgery | 1 day | Morphine consumption in the first 24 hours will be counted by IV patient controlled analgesia device (PCA). Patients will be able to request opioids via PCA device when the nrs score is above 4. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Post-operative acute pain | 1 day | Pain status will be evaluated based on NRS scores. Pain status will be evaluated at 1, 3, 6, 9, 12, 18, 24. hours after surgery. Each NRS is scores 0-10. (0=no pain ; 10=pain as bad as can be) |
Countries
Turkey (Türkiye)
Outcome results
None listed