Chronic Obstructive Pulmonary Disease
Conditions
Keywords
COPD, Exacerbation COPD, pulmonary rehabilitation, lung transplantation, acute exacerbation, waiting list, end-stage lung disease
Brief summary
Data from chronic obstructive pulmonary disease patients awaiting lung transplantation which performed a pulmonary rehabilitation program will be analyzed retrospectively. Acute exacerbations occur frequently in these patients and have a major impact on the course of the disease. This study investigates the prevalence and the impact of acute exacerbations during pulmonary Rehabilitation in patients with severe chronic obstructive pulmonary disease patients awaiting lung Transplantation that continued the Rehabilitation program despite an acute exacerbation. Data will be taken from the internal database of the reference center (Schoen Klinik Berchtesgadener Land, Schoenau, Germany) where these data were collected during clinical routine.
Interventions
OTHERPulmonary Rehabilitation
Patients performed a comprehensive pre-lung transplant inpatient pulmonary rehabilitation program for 4 to 5 weeks duration.
Sponsors
Schön Klinik Berchtesgadener Land
Klaus Kenn
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* confirmed diagnosis of chronic obstructive pulmonary disease including patients with alpha-1 antitrypsin deficiency * listed for lung Transplantation or in the Evaluation process for lung transplantation * performed a pulmonary rehabilitation program at the reference center
Exclusion criteria
* patients that discontinued the pulmonary Rehabilitation program due to any reason and could therefore not perform assessement tests at the end of regular Rehabilitation program
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change in 6-minute walk distance | day 1 and last day of pulmonary rehabilitation | The 6-minute walk test will be performed in accordance to the Guidelines of the European Respiratory Society and the American Thoracic Society |
| Change in Quality of life | day 1 and last day of pulmonary rehabilitation | health-related Quality of life will be assessed by the physical and mental health component score of the short form 36 health survey (score from 0 to 100 with higher scores indicating better quality of life) |
Countries
Germany
Outcome results
None listed