Hydrocephalus
Conditions
Keywords
neuroelectrophysiology, hydrocephalus, disorder of consciousness
Brief summary
The symptoms of hydrocephalus containing consciousness condition with muscle tone in some patients will be relieved, after the cerebrospinal fluid release test is carried out. Neuroelectrophysiology in patients with disorders of consciousness of post-traumatic hydrocephalus (PTH) can establish the association with consciousness and muscle tone to a certain extent, and predict the shunt effect of PTH with disorders of consciousness.
Interventions
None listed
Sponsors
Xiangya Hospital of Central South University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
16 Years to 70 Years
Healthy volunteers
No
Inclusion criteria
Patients with disorder of consciousness in traumatic brain injury. The presence of hydrocephalus through image examination.
Exclusion criteria
Patients who cannot tolerate shunt surgery. Sedation maintained by greater than 0.15mg/kg/hour of midazolam or the infusion dose of propofol higher than 4mg/kg/hour. Patients who are participating in drug research or other clinical trials.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Score of glasgow outcome scale in 6 months after shunt operation | 6 months |
Secondary
| Measure | Time frame |
|---|---|
| Score of glasgow outcome scale in 6 months after shunting under different ventricular pressure | 6 months |
| Revised coma recovery scale (CRS-R) in 1 week after shunting | 1 week |
| Modified Ashworth Scale (MAS) in 1 week after shunting | 1 week |
| Revised coma recovery scale (CRS-R) in 1 month after shunting | 1 month |
| Modified Ashworth Scale (MAS) in 1 month after shunting | 1 month |
Countries
United States
Contacts
Primary ContactJian Wang, master
Outcome results
None listed