Mental Disorder, Child
Conditions
Brief summary
The purpose of this study is to demonstrate an association between a biological pattern of dysregulation of the HPA axis and mental disorders in children exposed to early life stress.
Detailed description
The purpose of this study is to demonstrate an association between a biological pattern of dysregulation of the HPA axis and mental disorders in children exposed to early life stress. Cortisol secretion lead to define two groups : pathologic versus normal cortisol secretion. Mental disorders is evaluate with Mini-Kids II (a mental health questionary) and lead to define two groups : mental disorders versus no mental disorders
Interventions
BEHAVIORALMini Kid II
Mini Kid II (Mini International Neuropsychiatric Interview ) is a standardised, hetero mental health questionary for children, according to DSM IV. Mini Kid II will be administered to children between day 3 and 7 during the study.
Sponsors
University Hospital, Brest
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
OTHER
Masking
NONE
Intervention model description
The study is an monocentric, interventional, comparative uncontrolled study
Eligibility
Sex/Gender
ALL
Age
8 Years to 10 Years
Healthy volunteers
Yes
Inclusion criteria
* Aged 8 to over 10 years * To be entrust to ASE of Finistère in stable environment (the same place of residence since 6 months or more) * French speaking * Oral consent by children * Informed and signed consent by tenured of parent authority
Exclusion criteria
* Don't want to participate * To have chronic neurologic or endocrinal pathology or don't have access to verbal language.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Mini Kid II : Mini International Neuropsychiatric Interview | Day 10 to the study | Standardized questionary administered by a physician. There are 30 pages with 17 subjects like depression, maniac trouble, panic trouble, etc. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| CBCL score : Child Behaviour Check List | Day 10 to the study | CBCL Score is a hetero scale administered by host family or caseworker. It is a scale 0 (no behavior troubles) to 124 (behavior troubles). |
| BRIEF : Behavrioral Rating Inventory of Executive Function | Day 10 to the study | Standardized questionary administered by by host family or caseworker between day 4 and 13 to the study. BRIEF questionary contains 2 themes (metacognition and Behavior regulation) with 85 items in total. Each item contains 3 answers : Never (0)/ Sometime(1)/ Always(2) |
Countries
France
Outcome results
None listed