Patient Undergoing Diagnostic Coronary Angiography
Conditions
Brief summary
To investigate whether omitting systemic anticoagulation during transradial coronary angiography and/or a distal radial access reduce the risk of postprocedural radial artery occlusion
Interventions
OTHERDistal radial access
Distal radial access and No anticoagulation
Sponsors
University of Luebeck
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Clinical indication to perform diagnostic coronary angiography * Pretreatment with oral anticoagulants (phenprocoumon or direct oral anticoagulants \[dabigatran, apixaban, rivaroxaban, or edoxaban\]) * Age \> 18 years * Written informed consent
Exclusion criteria
* Already administered additional anticoagulation prior to coronary angiography * Planned coronary intervention * Preexisting radial artery occlusion or missing pulse at the potential puncture sites * Allergy / intolerance to anticoagulants * Active bleeding or comorbidity with elevated bleeding risk * Pregnancy * Inability to sign informed consent * Participation in another trial
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of postprocedural radial artery occlusion | Day 1 | Will be the occurrence of postprocedural radial artery occlusion assessed with high-resolution vascular ultrasound. Experienced sonographers will perform color Doppler ultrasound in all study patients after removal of the compression device to examine the radial, ulnar, and brachial arteries of the access forearm. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Sonographic characteristics of radial artery occlusion | 3 Month | Occlusion lengths or minimal residual perfusion |
Outcome results
None listed