The GErman Italian Spanish Takotsubo (GEIST) Registry

Conditions

Takotsubo Syndrome

Brief summary

GEIST is a multicenter, international observational registry of patients with Takotsubo syndrome. Data regarding the clinical profile (demographic characteristics, clinical presentation, laboratory measures, electrocardiography /echocardiography / coronary angiography parameters, treatment and medication), in-hospital course and complications and short-/long-term outcome are collected prospectively and retrospectively to increase the understanding of the disease.

Detailed description

The open-ended, multicenter, international GEIST registry collects data from patients with Takotsubo syndrome during the index hospitalization and follow-up. Furthermore, long-term outcome data are acquired with structured telephone interviews, in case patients do not undergo regular outpatient visits in the participating study centers. The GEIST registry retrospectively includes data, which have already been collected, and prospectively continues to enroll patients with newly diagnosed Takotsubo syndrome.

Santoro F, Arcari L, Núñez Gil IJ, Ragnatela I, Di Nunno N, El-Battrawy I, Guerra F, Novo G, Musumeci B, Cacciotti L, Mariano E, Parisi G, Montisci R, Marchetti MF, D'Alessandro D, Di Peppo M, Matera A, Gravina M, Uribarri A, Alfonso F, Mejía H, Blanco-Ponce E, Corbí-Pascual M, Akin I, Thiele H, Eitel I, Stiermaier T, Brunetti ND.

2025-11-13

10.1016/j.ijcard.2025.134014

Beta-Blockers and Long-Term Mortality in Takotsubo Syndrome

Sergio Raposeiras‐Roubín, Francesco Santoro, Luca Arcari, Ravi Vazirani, Giuseppina Novo et al. (27 authors)

JACC Heart Failure2025-02-0515 citations

10.1016/j.jchf.2024.11.015

Renin angiotensin system inhibitors and outcome in patients with takotsubo syndrome: A propensity score analysis of the GEIST registry.

Santoro F, Stiermaier T, Núñez Gil IJ, El-Battrawy I, Pätz T, Cacciotti L, Guerra F, Novo G, Musumeci B, Volpe M, Mariano E, Caldarola P, Montisci R, Ragnatela I, Cetera R, Vazirani R, Lluch C, Uribarri A, Corbi-Pascual M, Conty Cardona DA, Akin I, Barbato E, Thiele H, Brunetti ND, Eitel I, Arcari L.

2024-09-107 citations

10.1016/j.ahj.2024.08.019

Ibrahim El‐Battrawy, Francesco Santoro, Iván J. Núñez‐Gil, Toni Pätz, Luca Arcari et al. (26 authors)

Journal of the American Heart Association2024-02-1315 citations

10.1161/jaha.123.030623

Happy Heart Syndrome: Frequency, Characteristics, and Outcome of Takotsubo Syndrome Triggered by Positive Life Events.

Stiermaier T, Walliser A, El-Battrawy I, Pätz T, Mezger M, Rawish E, Andrés M, Almendro-Delia M, Martinez-Sellés M, Uribarri A, Pérez-Castellanos A, Guerra F, Novo G, Mariano E, Musumeci MB, Arcari L, Cacciotti L, Montisci R, Akin I, Thiele H, Brunetti ND, Núñez-Gil IJ, Santoro F, Eitel I.

2022-05-0426 citations

10.1016/j.jchf.2022.02.015

Incidence and Clinical Impact of Right Ventricular Involvement (Biventricular Ballooning) in Takotsubo Syndrome: Results From the GEIST Registry.

El-Battrawy I, Santoro F, Stiermaier T, Möller C, Guastafierro F, Novo G, Novo S, Mariano E, Romeo F, Romeo F, Thiele H, Guerra F, Capucci A, Giannini I, Brunetti ND, Eitel I, Akin I.

2021-05-2730 citations

10.1016/j.chest.2021.04.072

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

No

Inclusion criteria

* Patients with Takotsubo syndrome

Exclusion criteria

* Non

Design outcomes

Primary

Measure	Time frame	Description
All-cause mortality	Day 0	All-cause mortality (in-hospital, short-term, long-term)

Secondary

Measure	Time frame	Description
In-Hospital complications	Day 0	Cardiogenic shock, pulmonary edema, death, life-threatening arrhythmias, ventricular thrombus formation, right ventricular involvement

Countries

Germany, Italy

Contacts

Primary ContactIngo Eitel, Prof. Dr.

ingo.eitel@uksh.de004945150044501

Backup ContactThomas Stiermaier, Dr.

Outcome results