The COVID-19 ICU PRAYER Study

Impact of Multi-Denominational Prayer on Morbidity and Mortality of Patients Admitted to the Intensive Care Unite With Corona Virus Infection

Status

Terminated

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04361838

Enrollment

200

Registered

2020-04-24

Start date

2020-05-21

Completion date

2021-04-30

Last updated

2022-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronavirus Infection

Brief summary

This is a multicenter; double blind randomized controlled study investigating the role of remote intercessory multi-denominational prayer on clinical outcomes in COVID-19 + patients in the intensive care unit. All patients enrolled will be randomized to use of prayer vs. no prayer in a 1:1 ratio. Each patient randomized to the prayer arm will receive a universal prayer offered by 5 religious denominations (Christianity, Hinduism, Islam, Judaism and Buddhism) in addition to standard of care. Whereas the patients randomized to the control arm will receive standard of care outlined by their medical teams. During ICU stay, patients will have serial assessment of multi-organ function and APACHE-II/SOFA scores serial evaluation performed on a daily basis until discharge. Data assessed include those listed below.

Interventions

BEHAVIORALprayer

receive prayers daily while in ICU

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

DOUBLE (Subject, Caregiver)

Eligibility

Sex/Gender

ALL

Age

18 Years to 110 Years

Healthy volunteers

Inclusion criteria

* Male or female greater than 18 years of age * Confirmed positive for COVID-19 * Patient admitted to Intensive Care Unit

Exclusion criteria

* Patients admitted to ICU for diagnosis that is not COVID-19 positive.

Design outcomes

Primary

Measure	Time frame	Description
Impact of multi-denominational prayer on clinical outcomes of critically ill COVID-19 patients in the Intensive Care Unit on mortality.	daily until patient recovers and moves out of ICU or exits the study, up to 30 days	This study will measure the difference in mortality of COVID-19 patients who are admitted to ICU - given prayer vs no prayer as an adjunct to standard therapy.

Secondary

Measure	Time frame	Description
Difference in patient outcomes - Acute Physiology and Chronic Health Enquiry. APACHE II score.	daily until patient recovers and moves out of ICU or exits the study, up to 30 days.	APACHE II uses 0-71 scale, the higher the score the higher the risk for mortality.
Difference in patient outcomes - Sequential Organ Failure Assessment - SOFA Score	daily until patient recovers and moves out of ICU or exits the study, up to 30 days	The higher the SOFA score the increased likelihood of organ failure.
Difference in patient outcomes - Length of stay in ICU.	daily until patient recovers and moves out of ICU or exits the study, up to 30 days	A prolonged length of time in ICU increases mortality.
Difference in patient outcomes - Length of ventilator support	daily until patient recovers and moves out of ICU or exits the study, up to 30 days	A prolonged length of time with ventilator support increases mortality.
Difference in patient outcomes - length of vasopressor support	daily until patient recovers and moves out of ICU or exits the study, up to 30 days	A prolonged length of time with vasopressor support increases recovery time.

Countries

United States

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026