Observing the Morphology of Schlemm's Canal and Crystalline Lens in Different Age

Morphology of Schlemm's Canal and Crystalline Lens in Different Age: a Swept-source Optical Coherence Tomography Study

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04360161

Enrollment

Registered

2020-04-24

Start date

2019-08-08

Completion date

2020-01-20

Last updated

2020-04-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Schlemm's Canal Occlusion

Brief summary

The aim of this study is to quantify and observe the morphology of trabecular meshwork (TM), Schlemm's canal (SC), ciliary body and crystalline lens before and after cycloplegia in patients with different ages using swept-source optical coherence tomography.

Interventions

DEVICEswept-source optical coherence tomography

Aswe pt-source OCT (CASIA SS-1000; Tomey Corporation, Nagoya, Japan), which is specifically designed for anterior segment imaging using a 1310 nm wavelength with a scan speed of 30,000 A-scans per second and an axial resolution of \<10 μm.

Study design

Allocation

Intervention model

SINGLE_GROUP

Primary purpose

PREVENTION

Masking

NONE

Eligibility

Sex/Gender

ALL

Age

7 Years to 60 Years

Healthy volunteers

Yes

Inclusion criteria

* healthy patients who can cooperated with the swept-source OCT measurements

Exclusion criteria

* history of ocular disease * presence of central nervous system or systemic disease

Design outcomes

Primary

Measure	Time frame	Description
area of Schlemm's canal and trabecular meshwork	up to 6 months	The area of Schlemm's canal and trabecular meshwork was manually measured and the relationship between the parameters and age was analyzed.

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026