Coronaviridae Infections, Coronavirus, Coronavirus 19, Coronavirus-19, Corona Virus Infection, COVID, COVID 19, COVID-19, Gastrointestinal Microbiome, Gut Microbiome
Conditions
Keywords
Microbiome, Coronavirus, Corona Virus, 19, COVID, COVID-19
Brief summary
This study seeks to determine whether the virus which causes COVID-19, SARS-CoV-2, is shed in the stools of patients who are infected.
Detailed description
In this study the stool of patients who are being treated for COVID-19 will be tested during treatment and then again following treatment to determine if the virus is shed in the stool during infection, afterwards, or both.
Interventions
There is no intervention in this study
Sponsors
ProgenaBiome
Study design
Observational model
OTHER
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
1. Signed informed consent, demonstrating that the patient understands the procedures required for the study and the purpose of the study 2. Male or female of 18 years of age or older 3. Diagnosis of COVID-19 infection by RT- PCR within 1 week of Screening
Exclusion criteria
1. Refusal to sign informed consent form 2. History of bariatric surgery, total colectomy with ileorectal anastomosis or proctocolectomy. 3. Postoperative stoma, ostomy, or ileoanal pouch 4. Treatment with total parenteral nutrition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Correlation of Microbiome to Disease via Relative Abundance Found in Microbiome Sequencing | One year | Relative abundance of bacterial classes within taxonomic phyla and, more broadly, within their domain will be analyzed by sequencing the gut microbiome. These data will then be categorized among specific gastrointestinal disease types. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Validation of Sequencing Methods | One year | To validate the methods used to sequence samples |
Countries
United States
Contacts
Primary ContactSabine Hazan, MD
Backup ContactJordan Daniels, MS
Outcome results
None listed