Frozen Embryo Transfer
Conditions
Brief summary
The study focus on the impact of estrogen/progesterone substitution during artificial cycle frozen embryo transfer (AC-FET) in women undertaking assisted reproductive technology treatment (ART).
Detailed description
The aim is to investigate whether the coagulation is activated in women undergoing estrogen/progesterone substitution during artificial cycle frozen embryo transfer (AC-FET) in assisted reproductive technology treatment (ART). An activation of the coagulation might induce an increased thromboembolic risk in these women. Thus, the present study may lead to improvement of the current treatment protocol for women receiving AC-FET and ultimately prevent thromboembolic complications for woman in fertility treatment.
Interventions
DIAGNOSTIC_TESTPrimary and secondary hemostasis
Focus on platelet aggregation, primary and secondary hemostasis parameters
Sponsors
Aarhus University Hospital
Horsens Hospital
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to 50 Years
Inclusion criteria
* Women receiving FET with or without estrogen/progesterone substitution
Exclusion criteria
* Known bleeding disorder * Indication for thromboprophylaxis during ART treatment * Treatment with anti-platelet medication including non-steroid-anti-inflammatory drugs (NSAIDs) within the last week * Donor recipients
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| coagulation | 1 year | Primary and secondary hemostasis parameters |
Countries
Denmark
Outcome results
None listed