Current Vaper, Healthy Subject
Conditions
Brief summary
This trial studies consumer assessments of tobacco flavor and odor. This study will compare the ability of expert and consumer panels to identify and characterize flavors, determine threshold detection levels for individual and mixed flavors, and identify the dominant flavor of mixtures.
Detailed description
PRIMARY OBJECTIVE: I. Develop consumer (untrained) sensory panels to identify and assess characterizing flavors in electronic (e)-liquids. OUTLINE: Non-user panelists smell and user panelists puff flavored e-liquids and answer questions about the products.
Interventions
BEHAVIORALBehavioral Intervention
Smell or puff e-liquids
OTHERQuestionnaire Administration
Ancillary studies
Sponsors
National Cancer Institute (NCI)
University of Rochester
Roswell Park Cancer Institute
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
21 Years to 55 Years
Healthy volunteers
Yes
Inclusion criteria
* CONSUMER USER: Current daily vapers of products containing nicotine * CONSUMER USER: No concurrent use of other tobacco products * CONSUMER USER: General good health * CONSUMER USER: No allergies * CONSUMER USER: No self-reported taste or smell deficits * CONSUMER USER: Not pregnant or lactating * CONSUMER USER: No medications known to interfere with taste/smell * CONSUMER USER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER USER: No positive diagnosis of COVID-19 within 30 days * CONSUMER NONUSER: No use of tobacco or nicotine products in the last year * CONSUMER NONUSER: General good health * CONSUMER NONUSER: No allergies * CONSUMER NONUSER: No self-reported taste or smell deficits * CONSUMER NONUSER: Not pregnant or lactating * CONSUMER NONUSER: No medications known to interfere with taste/smell * CONSUMER NONUSER: Passing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER NONUSER: No positive diagnosis of COVID-19 within 30 days
Exclusion criteria
* CONSUMER USER: Outside age range * CONSUMER USER: Not current daily vapers * CONSUMER USER: Concurrent use of other tobacco products * CONSUMER USER: Fair or poor general health * CONSUMER USER: Allergies * CONSUMER USER: Self-reported taste or smell deficits * CONSUMER USER: Pregnant or lactating * CONSUMER USER: Medications known to interfere with taste/smell * CONSUMER USER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER USER: Positive diagnosis of COVID-19 within 30 days * CONSUMER NONUSER: Outside age range * CONSUMER NONUSER: Use of tobacco or nicotine products in the last year * CONSUMER NONUSER: Fair or poor general health * CONSUMER NONUSER: Allergies * CONSUMER NONUSER: Self-reported taste or smell deficits * CONSUMER NONUSER: Pregnant or lactating * CONSUMER NONUSER: Medications known to interfere with taste/smell * CONSUMER NONUSER: Failing scores on the Brief Smell Identification Test (B-SIT), phenylthiocarbamine (PTC) and 6-n-propylthiouracil (PROP) smell and taste tests * CONSUMER NONUSER: Positive diagnosis of COVID-19 within 30 days
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Flavor identification and evaluation | Up to 12 months | Subjects will be asked to identify various concentrations of flavored e-liquids |
| Specific flavor detection thresholds | Up to 12 months | Subjects will rate intensity of odors of e liquids |
| Flavor combination thresholds | Up to 12 months | Subjects will rate a combination of two e-liquids combined |
Countries
United States
Outcome results
None listed