Assessment of Serum Levels of Vitamin D, Vitamin B12 and Folic Acid Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.

Vitamin D, Vitamin B12, and Folic Acid Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04355949

Acronym

Enrollment

Registered

2020-04-21

Start date

2020-02-28

Completion date

2020-06-30

Last updated

2021-01-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vitamin D, Vitamin B12 and Folic Acid Among Patients With Premature Ejaculation

Keywords

Premature Ejaculation

Brief summary

Therefore, this study will aim to assess serum levels of vitamin D, vitamin B12 and folic acid among patients with lifelong PE and non-responding to dapoxetine treatment.

Detailed description

We will consider the patients with LPE non-responding to dapoxetine treatment when they used the optimum dose (30 and 60mg) dapoxetine for 4 separate times with no response. Serum vitamin D, vitamin B12, and folic acid levels will be assessed in all subjects included in the study. Venous blood samples will be drawn and kept into EDTA bottles in the morning between 8 and 10 a.m. after an overnight fast of about 10-14 hr.

Interventions

DIAGNOSTIC_TESTSerum vitamin D, vitamin B12, folic acid

Serum vitamin D, vitamin B12, and folic acid levels will be assessed

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

DIAGNOSTIC

Masking

SINGLE (Investigator)

Masking description

In a case-controlled clinical study, it will be carried out on 30 patients with lifelong PE and 30 healthy control subjects. Serum vitamin D, vitamin B12, and folic acid levels will be assessed in all subjects included in the study.

Intervention model description

assess serum levels of vitamin D, vitamin B12 and folic acid among patients with lifelong PE and non-responding to dapoxetine treatment.

Eligibility

Sex/Gender

MALE

Age

20 Years to 50 Years

Healthy volunteers

Yes

Inclusion criteria

* premature ejaculation * non-responding to dapoxetine treatment.

Exclusion criteria

* diabetes mellitus, * chronic prostatitis, * Advanced renal or hepatic diseases * neurological diseases and * C.N.S. medications

Design outcomes

Primary

Measure	Time frame	Description
Serum vitamin D in patient with PE	0-1 week	Serum vitamin D levels will be assessed Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.
vitamin B12, in patient with PE	0-1 week	vitamin B12 levels will be assessed Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.
folic acid in patient with PE	0-1 week	folic acid levels will be assessed Among Patients With Lifelong Premature Ejaculation and Non-responding to Dapoxetine Treatment.

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026