Sarcopenia
Conditions
Brief summary
Most previous clinical trials that addressed exercise for sarcopenic elderly subjects focused on community-dwelling older adults who were relatively healthy. There is a notable paucity of high-quality research investigating the effects and feasibility of exercise for hospitalized or institutionalized older people, who are generally frailer and more severe in functional impairment than those living in the community. Moreover, most reported exercise programs were of long-term duration, which typically lasted 3 to 6 months with two sessions per week. It remains unclear whether short-term exercise would be effective for treating sarcopenia. Therefore, the investigators aimed to assess the effectiveness of short-term exercise for treating sarcopenia in hospitalized older patients aged 80 years and over.
Interventions
BEHAVIORALbalance training
The training to improve balance is to work on the core muscle groups that help to maintain your posture.,and increase muscular strength.
BEHAVIORALresistance training
Resistance training is a form of exercise that improves muscular strength and endurance. During a resistance training workout, you move your limbs against resistance provided by your body weight, gravity, bands, weighted bars or dumbbells.
BEHAVIORALaerobic exercise
Aerobic exercise is any activity that gets your blood pumping and large muscle groups working. It's also known as cardiovascular activity.
BEHAVIORALusual care
received usual care
Sponsors
Yuxiang Liang
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
80 Years to 102 Years
Healthy volunteers
No
Inclusion criteria
1. aged ≥80 years; 2. being able to ambulate (assistance was acceptable); 3. being able to communicate and collaborate with the physiotherapist; 4. with sarcopenia defined by the AWGS criteria ;
Exclusion criteria
1. terminal illness; 2. uncontrolled heart failure; 3. myocardial infarction within the past three months; 4. uncontrolled respiratory failure; 5. bone fractures within the past three months; 6. acute pulmonary embolism; 7. major surgery within the past three months; 8. uncontrolled arrhythmia; 9. refusal to participate in this study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of activities of daily living from the baseline to the end of the 2-week intervention | 2 weeks | Basic activities of daily living (BADL) assessed by Barthel Index. The total score for Barthel Index ranges from 0 (worst) to 100 (best) points. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The change of gait speed | 2 weeks | Gait speed was measured using a 4-meter walking test. |
| The change of handgrip strength | 2 weeks | Handgrip strength was measured using a digital grip dynamometer |
| The change of the score of Short Physical Performance Battery | 2 weeks | The Short Physical Performance Battery (SPPB) is an objective assessment tool for evaluating lower extremity functioning in older persons. The total score for SPPB ranges from 0 (worst) to 12 (best) points. |
| The change of the score of Timed Up and Go test | 2 weeks | The Timed Up and Go test (TUG) is a simple test used to measure basic functional mobility and safety with mobility. The score for the TUG is the time consumption of the whole process. The longer time consuption indicates the more worse outcome. |
Outcome results
None listed