Dry Age-related Macular Degeneration
Conditions
Keywords
Dry AMD
Brief summary
The purpose of this study is to assess the vision improvement achieved by patients with late stage dry age-related macular degeneration who received corneal treatments by a low vision aid device.
Detailed description
The purpose of this study is to assess the vision improvement achieved by patients with late stage dry age-related macular degeneration who received corneal treatments by a low vision aid device. Patient records for patients with at least 12 months follow-up will be analyzed to determine measures of vision improvement including best spectacle-corrected distance and near visual acuity. Analyses will include descriptive statistics and correlation between outcomes and baseline characteristics.
Interventions
Near infrared light is used to irradiate the cornea to change the modulus of small volumes of anterior stroma. The change of modulus produces a change of corneal stiffness and shape that modifies the distribution of light onto the retina. Light rays are redirected from dysfunctional areas of the retina that have been damaged by age-related macular degeneration (AMD) to functional areas of the retina, thereby improving patient vision.
Sponsors
Bochner Eye Institute
Optimal Acuity Corporation
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
50 Years to 100 Years
Healthy volunteers
Yes
Inclusion criteria
1. \- Male or female 2. \- Any race 3. \- Patient is at least 50 years old 4. \- Patient has diagnosed late stage dry age-related macular degeneration in one or both eyes. 5. \- Treated eyes were pseudophakic at the time of treatment. 6. \- Patient had moderate to severe baseline vision impairment with best spectacle-corrected distance visual acuity (CDVA) of 20/63 or worse (decimal = 0.317 or less; logMAR greater than or equal to 0.50) in the treated eye(s). 7. \- Patient CDVA records are available at baseline and at 12 month post-treatment.
Exclusion criteria
1. \- Corneal disease or disorder in either eye. 2. \- Increased intraocular pressure (above 20 mm Hg), glaucoma or history of glaucoma. 3. \- Presence or history of any other condition or finding that, in the opinion of the investigator, makes the patient unsuitable for retrospective observational study. \-
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| CDVA | 12 months | Best spectacle-corrected distance visual acuity (CDVA) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| CNVA | 12 months | Best spectacle-corrected near visual acuity (CNVA) |
Countries
Canada
Outcome results
None listed