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Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia

Preoperative, Intraoperative and Postoperative Predictors of Post-clamping Neurologic Deficits During Carotid Endarterectomy With Regional Anesthesia

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04347785
Enrollment
206
Registered
2020-04-15
Start date
2011-01-01
Completion date
2030-12-31
Last updated
2020-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Carotid Endarterectomy

Keywords

Carotid Stenosis, regional anesthesia

Brief summary

Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established. The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated.

Detailed description

Patients undergoing carotid endarterectomy may suffer from neurologic deficits (ND) during the carotid cross-clamping due to cerebral hypoperfusion. An associated risk of postoperative stroke incidence is also well established. The aim of this study is to evaluate the predictive factors associated with ND during CEA performed with RA. The perioperative implications of the ND were also evaluated. All consecutive patients from a tertiary referral center who underwent CEA for carotid artery stenosis (CS) and consecutive patients who presented alterations in the neurologic examination after ICA clamping during CEA are selected. The control patients, submitted to the same procedure but with no neurologic alterations, are consecutively selected.

Interventions

PROCEDUREcarotid endarterectomy

shunt

Sponsors

Universidade do Porto
Lead SponsorOTHER

Study design

Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 100 Years
Healthy volunteers
No

Inclusion criteria

* carotid endarterectomy under regional anesthesia * Postclamping carotid deficit

Exclusion criteria

* carotid stenting

Design outcomes

Primary

MeasureTime frameDescription
Strokeup to 5 yearsAn episode of neurological dysfunction caused by focal cerebral, spinal, or retinal infarction.

Secondary

MeasureTime frameDescription
Clavien-Dindo Classification >330 daysPostoperative event life threatining and requiring surgical, endoscopic or radiological intervention

Other

MeasureTime frameDescription
Major adverse cardiosvascular and cerebrovascular eventsup to 5 yearsAMI, Stroke, AHF hospitalization, MALE, MACE, All-cause mortality

Countries

Portugal

Contacts

Primary ContactJoao P Rocha-Neves, MD, MSC; MPH, FEBVS
joaorochaneves@hotmail.com+351910486230

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026