Cardiac Resynchronization Therapy
Conditions
Keywords
non invasive mapping, cardiac resynchronization therapy, pacing-induced cardiomyopathy, electrical shock
Brief summary
Non-invasive mapping using the Cardio Insight system is performed in heart failure patients requiring biventricular pacing to optimize therapy, and understand mechanisms underlying pacing-induced cardiomyopathy and ventricular arrhythmias.
Detailed description
Non-invasive mapping using the Cardio Insight system is prospectively performed routinely in heart failure patients requiring cardiac resynchronization therapy. Control patients are included, requiring chronic permanent right ventricular pacing. Specific focus include: optimization of programming parameters, pacing-induced cardiomyopathy, ventricular arrhythmias, defibrillation threshold testing and electrical shocks.
Interventions
DIAGNOSTIC_TESTNon invasive epicardial mapping
Non invasive mapping using Cardio Insight system is performed in all included patients.
Sponsors
University Hospital, Tours
Study design
Observational model
CASE_CONTROL
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients implanted with a biventricular pacing device (CRT) device * Patients chronically implanted with a right ventricular pacing device.
Exclusion criteria
* Age \<18 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Ventricular activation map | Up to 6 months | Differences (qualitative and quantitative measurements) in ventricular activation patterns are identified. |
| Response to CRT | Up to 2 years | Composite endpoint : volumetric response, heart failure hospitalizations, and all-cause mortality. |
Countries
France
Outcome results
None listed