Depressive Symptoms
Conditions
Keywords
Depression, Cognitive control, Emotion, Working memory, Cognitive bias, Emotional regulation
Brief summary
The purpose of this study is to test whether emotional working memory training and attention bias modification training are an effective neurobehavioral therapy to improve depressive symptoms.That is whether emotional working memory training is superior to attention bias modification training or not in reducing depressive symptoms over 1 year after training.
Detailed description
Attentional bias has been theorized to play a critical role in the onset and maintenance of depression. Attentional bias modification training (ABMT), an experimental paradigm that uses training to induce adaptive attentional bias, was developed to test the causal model and this has therapeutic implications in depression.To test the effect of ABMT on treatment of depressive symptoms, a randomized, double-blind, placebo and blank controlled trial is conducted in college students who are experiencing mild-to-severe symptoms of depression.
Interventions
BEHAVIORALWorking memory training
Participants complete 10 sessions of maintaining positive working memory training during a two-week period. Each session consists of 15 blocks.
BEHAVIORALPositive ABMT
Participants complete 8 sessions of attention bias modification training (ABMT) during a two-week period. Each session consists of 218 trials, and the time to complete a training session is 12 minutes.
Sponsors
Hunan Normal University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
TRIPLE (Subject, Investigator, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
16 Years to 21 Years
Healthy volunteers
Yes
Inclusion criteria
Meet the major and mild depression disorder's criteria
Exclusion criteria
bipolar disorder, schizophrenia or organic mental disorder; any concurrent psychotherapy; any concurrent psychotropic medication.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Changes of depressive symptoms | pre-training, post-training(2 weeks after pre-training), follow-ups(1-week,2-week,4-week,7-week,3-month( booster pre-training), 4-month (booster post-training), 5-month,6-month,12-month after post-training) | Depression symptoms tested by clinicians using the Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children (K-SADS) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Changes of self-reported depressive symptoms | pre-training, post-training(2 weeks after pre-training), follow-ups(1-week,2-week,4-week,7-week,3-month( booster pre-training), 4-month (booster post-training), 5-month,6-month,12-month after post-training) | Self-reported depressive symptoms assessed by Beck depression scale-second version (BDI-II) |
Countries
China
Outcome results
None listed