Effectiveness of Vapocoolant Spray on Venipuncture Pain in Young Male Donors

Status

Completed

Phases

Study type

Interventional

Source

ClinicalTrials.gov

Registry ID

NCT04346732

Enrollment

Registered

2020-04-15

Start date

2016-04-01

Completion date

2016-06-30

Last updated

2020-04-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Venipuncture, Pain

Keywords

Vapocoolant Spray, Venipuncture, Pain, Donors

Brief summary

Aim: The aim of this study is to assess the effectiveness of vapocoolant spray in reducing pain related to venipuncture in young, healthy male blood donors. Hypotheses: H1: Vapocoolant spray reduces venipuncture pain during blood donation. H0: Vapocoolant spray does not reduce venipuncture pain during blood donation.

Detailed description

After being informed about the study and potential risks, all patients giving written informed consent. Before the procedure was begun, the donors who agreed to participate in the study were met face-to-face and asked to fill in the Informative Characteristics Form, the VAS, the Blood/Injection Fear Scale and the STAI-I forms.Then the donors were assigned to their groups by the researcher.The donors in the control group were not given any intervention during the blood collection process. Vapocoolant spray was applied to the donors in the vapocoolant spray group. During the blood collection procedure, after the donors' skin was cleaned with antiseptic solution, spray was applied to the application site for a maximum of 10-15 seconds from a distance of 25 cm. In both groups, immediately following venipuncture, pain assessment was made with the VAS by the researcher, who did not know which group each participant belonged to.

Interventions

OTHERVapocoolant spray

Vapocoolant spray

Study design

Allocation

RANDOMIZED

Intervention model

PARALLEL

Primary purpose

SUPPORTIVE_CARE

Masking

SINGLE (Investigator)

Masking description

In both groups, immediately following venipuncture, pain assessment was made with the VAS by the researcher, who did not know which group each participant belonged to.

Intervention model description

The participants were separated into two groups with the randomisation method.These groups were named the vapocoolant spray group and the control group

Eligibility

Sex/Gender

MALE

Age

18 Years to 35 Years

Healthy volunteers

Yes

Inclusion criteria

* aged between 18 and 35 * BMI between 18.5 and 24.9 kg/m2 * speaks turkish * male donor * individuals who applied to make voluntary blood donations * volunteers to participate in the study

Exclusion criteria

* donors who did not agree to take part in the study, * donors with open wound, scar, infection, dermatitis, eczema or lesion at the venipuncture site, or donors with cold allergy

Design outcomes

Primary

Measure	Time frame	Description
Change from baseline in venipuncture pain on the Visual Analogue Scale(VAS) during blood donation	immediately following venipuncture procedure	The VAS is used to inquire about pain levels resulting from venipuncture.In the 10 cm-long VAS, 0 indicates no pain, while 10 indicates the most intense pain.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026