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Longitudinal MRI Assessment in Patients With Diffuse Low-grade Gliomas

Retrospective Longitudinal Follow-up in Patients With Diffuse Low-grade Glioma With Multimodal MRI Assessment

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04346472
Acronym
SPECIFY
Enrollment
200
Registered
2020-04-15
Start date
2016-03-01
Completion date
2020-01-30
Last updated
2020-04-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low-grade Glioma

Keywords

Glioma, Magnetic Resonance Imaging, Magnetic Resonance Angiography, Disease Progression, Supratentorial Neoplasms, Blood Volume, Contrast Media, Gadolinium DTPA, Image Processing, Computer-Assisted, Neovascularization, Pathologic, Diffuse low grade glioma, Relative regional cerebral blood volume ( rRCBV), Early prognosis of anaplasic transformation, Diffuse low grade glioma anaplasic transformation

Brief summary

Retrospective longitudinal follow-up in patients with diffuse low-grade glioma with multimodal MRI assessment

Interventions

OTHERRepeated Measurements of the relative regional cerebral blood volume

Repeated Measurements of the relative regional cerebral blood volume variation through an every 6 monts Magnetic Resonance Imaging use.

Sponsors

University Hospital, Montpellier
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Initial WHO grade II * At least 3 exploitable MRI each including a morphologic FLAIR sequence and perfusion imaging

Exclusion criteria

-Major protected person ( trusteeship, curatorship, justice safeguard)

Design outcomes

Primary

MeasureTime frameDescription
Longitudinal variation of the relative regional cerebral blood volume1 dayLongitudinal variation of the relative regional cerebral blood volume from first pass perfusion imaging data for each MRI performed

Secondary

MeasureTime frameDescription
Collection of histological1 dayCollection of histological
Collection of radiological1 dayCollection of radiological
Collection of clinical varaibles1 dayCollection of clinical varaibles

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026