Excision Margin
Conditions
Keywords
Gastrointestinal stromal tumour, Coincidental GIST with LSG, Gastric GIST
Brief summary
LSG is thought to be the best choice for obese patients with conincidental GISTs, as a tumour can be resected along with resecting the stomach within the same procedure. The primary endpoint is that, how much does GIST suppose to be far from a staple line to do safe laparoscopic sleeve gastrectomy
Detailed description
The incidence of unsuspected GIST in LSG specimens in our series was high in comparison to cases reported in the literature. GISTs could be safely removed laparoscopically during LSG surgery with negative microscopic resection margins, with 1-2cm safety margin. Margins less than 1cm, high mitotic rate are adverse prognostic factors. Examining the whole stomach before resection is mandatory and can easily be done during LSG, GIST can be removed safely with LSG
Interventions
PROCEDURELaparoscopic sleeve gastrectomy
Excision of Gastric GIST along fundus or body of stomach in the same specimen of LSG with safety margin 1-2cm
Sponsors
Bassem Mohamed Sieda
Study design
Intervention model
SEQUENTIAL
Primary purpose
TREATMENT
Masking
NONE
Masking description
With institutional review board approval from Zagazig University Hospitals 338. A double-centre prospective study was conducted on prospectively collected data of all morbidly. 17 patients in Zagazig University Hospitals, Faculty of Medicine, Egypt and 321 patients done in bariatric surgery excellence unit in a tertiary hospital in Riyadh-KSA.
Intervention model description
With institutional review board approval from Zagazig University Hospitals 338. A double-centre prospective study was conducted on prospectively collected data of all morbidly. 17 patients in Zagazig University Hospitals, Faculty of Medicine, Egypt and 321 patients done in bariatric surgery excellence unit in a tertiary hospital in Riyadh-KSA.
Eligibility
Sex/Gender
ALL
Age
21 Years to 42 Years
Healthy volunteers
No
Inclusion criteria
All morbid obese patients with BMI more than 35
Exclusion criteria
* previous gastric surgery * patients with hiatus hernia * age under 21 years
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Excision of GIST during LSG | 4 years from start of study | we analyzed the incidence of GISTs in patients underwent LSG and investigated whether simultaneous resection can be oncologically adequate. as long as GIST is distal to staple line with a negative margin, laparoscopic sleeve gastrectomy can be done safely. |
Countries
Saudi Arabia
Outcome results
None listed