Retinoblastoma
Conditions
Brief summary
Retinoblastoma is the most common pediatric eye malignancy and manifests between 1 and 5 years of age. The tumor is most often diagnosed by leukocoria ( white reflex in the pupil). There is often a significant delay in diagnosis and early diagnosis enables good life prognosis and better vision outcome.There is currently not a standardized screening protocol for detection of retinoblastoma. Vision screening methods are recommended for children 3-5 years of age. The investigators are attempting to use instrument based screening started from birth to detect leukocoria.
Interventions
DEVICEPhotoscreening -
external picture taken with a an phone based app
Sponsors
Phoenix Children's Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Intervention model description
Single visit cross sectional prospective study
Eligibility
Sex/Gender
ALL
Age
0 Years to 10 Years
Healthy volunteers
Yes
Inclusion criteria
* Age birth to 10 years * Informed consent given by parent or legal guardian
Exclusion criteria
* None
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Reliability to detect leukocoria | 1 year | Testing the reliability of the app to detect leukocoria with good sensitivity and specificity |
Outcome results
None listed