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The Association Between MIH and HSPM

The Association Between MIH and HSPM

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT04344340
Enrollment
190
Registered
2020-04-14
Start date
2021-06-01
Completion date
2022-03-01
Last updated
2023-01-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypomineralization Molar Incisor, Hypomineralization of Enamel

Keywords

HSPM & MIH

Brief summary

Aim of the Study Evaluate association between HSPM and MIH in Egyptian children. Record the prevalence of HSPM and MIH in Egyptian children

Detailed description

Statement of the Problem: Molar Incisor Hypomineralization (MIH) is defined as developmental qualitative defect of systemic origin, which affects one to four of first permanent molars and frequently associated with permanent incisors . The prevalence of MIH worldwide was reported from 2.4% to40.2% and clinical measures of MIH based on scientific criteria was established based on the European Academy of Pediatric Dentistry criteria to allow comparison between the findings of different studies . The most commonly reported clinical problems for patients with MIH are hypersensitivity of teeth to various thermal and mechanical stimuli result in improper tooth brushing, plaque accumulation and rapid caries progression. Severely affected enamel shows post eruptive breakdown and such teeth require extensive treatment, ranging from prevention to restorations and extractions. MIH patients also have increased risk of developing dental fear and anxiety as well as behavior management problems added to the difficulty to achieve effective local anaesthesia which are related to chronic pulp inflammation from dentin exposure due to excessive enamel breakdown. Rational As developmental of Second Primary Molar start at the same time as the development of the first permanent molars and incisor but the maturation of permanent teeth occur more slow. So when a systemic disturbance occur it affect second primary molar as well as first permanent molar and incisors. Few studies test the association between hypomineralized second primary molar (HSPM) and MIH. While no study available on Egyptian children.

Interventions

DIAGNOSTIC_TESTclinical examination

clinical examination

Sponsors

Cairo University
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
8 Years to 9 Years

Inclusion criteria

* Children aged from 8 to 9 years. * Both genders. * No systemic health problems

Exclusion criteria

* Children with extracted primary second molars and permanent incisors and molars. * Children with history of dental trauma. * Children with orthodontic bands or dental appliances

Design outcomes

Primary

MeasureTime frameDescription
The prevalence of hypomineralized second primary molars.1 yearThe percentage of children who has enamel defect on their second primary molars in the study

Secondary

MeasureTime frameDescription
the prevalence of Molar Incisor Hypomineralization1 yearThe percentage of children who has enamel defect on their permenant molars and Incisors at this study

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026