COVID, Infection, Hospital, Infection Viral
Conditions
Keywords
Cardiology department, Medicine conventional department
Brief summary
The COVID-19 pandemic of SARS CoV2 (Severe Acute Respiratory Syndrome, COVID-19) infection, which is currently evolving in France, raises many questions about the clinical and biological profile of infected hospitalized patients. If certain biological factors like troponin, BNP (Brain Natriuretic Peptid), or clinical factors like cardiovascular history or oncological history are associated with a worse prognosis, available data comes from studies in Asia for the majority, or including a limited number of patients. Patient stratification remains a major issue for patient sorting and early referral of patients.
Detailed description
This study is observational, multicenter and retrospective, and is conducted in hospitals in France. Clinical data relating to history, comorbidities, risk factors, previous treatments, treatments during the hospitalization and treatments at the discharge from hospital, clinical parameters, biological and ultrasound cardiological data, procedures and events during hospitalization will be recorded, in order to identify the early predictors of clinical worsening in patients hospitalized for COVID-19 in cardiology or conventional medicine department.
Interventions
None listed
Sponsors
Institut National de la Santé Et de la Recherche Médicale, France
French Cardiology Society
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
\- Patients hospitalized in cardiology unit or medicine conventional sector with diagnosis of COVID-19 (positive PCR (Polymerase Chain Reaction) or diagnosis presumed by the clinical and radiographic picture)
Exclusion criteria
* Minors * Pregnant women
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Death rate | Through study completion, an average of 4 weeks | Analysis of all-cause death in relation with clinical patient profile |
| Transfer to intensive care unit | Through study completion, an average of 4 weeks | Correlation between clinical patient profile and transfer need to intensive care unit |
| Ventilation analysis | Through study completion, an average of 4 weeks | Type of ventilation procedures needed during the hospitalization (Orotracheal intubation for mechanical ventilation or Non-invasive ventilation or 29/5000 high flow oxygen therapy - Optiflow) in relation with clinical patient profile |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Construction of a predictive score for COVID-19 severe form | Through study completion, an average of 4 weeks | Description of clinical and biological patient profile leading to a worse prognosis |
Countries
France
Outcome results
None listed