Acute Interstitial Nephritis, Acute Kidney Injury, Kidney Diseases
Conditions
Keywords
Kidney, Kidney Disease, Acute Kidney Injury, Kidney biopsy, Kidney Biorepository
Brief summary
To support advances in the understanding of pathophysiology and therapies of kidney diseases by creating a BioBank of kidney tissue, DNA, plasma, and urine from patients with kidney diseases.
Detailed description
A biorepository of human samples to support research to advance understanding of human kidney diseases will be created. Clinically, kidney diseases are detected by blood and urine laboratory tests. However, the underlying cause of kidney disease is often not clear on blood and urine tests. In such cases, a clinician may choose to perform a kidney biopsy to establish the diagnosis. Patients who are scheduled to undergo a kidney biopsy will be invited to participate in this proposed study.
Interventions
None listed
Sponsors
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Yale University
Study design
Observational model
OTHER
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 99 Years
Healthy volunteers
No
Inclusion criteria
* Patients scheduled to undergo a clinically indicated kidney biopsy * English or Spanish speaking
Exclusion criteria
* Under 18 years or age * Known pregnancy * Additional vulnerable individuals (incarcerated, institutionalized, or otherwise unable to participate in the study) * Inability to provide informed consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Histological diagnosis | 5 years | Histological diagnosis of kidney disease determined by evaluation by renal pathologists |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Occurrence of chronic kidney disease, end stage kidney disease or death | 10 years | Track outcomes in participants recruited for up to 10 years |
Countries
United States
Outcome results
None listed